MGI, Mouse Genome Informatics, Jackson Labs(http://www.informatics.jax.org)
Mouse Genome Informatics (MGI) provides integrated access to data on the genetics, genomics, and biology of the laboratory mouse
RGD, Rat Genome Database, Medical College of Wisconsin(http://rgd.mcw.edu/)
The Rat Genome Database (RGD) curates and integrates rat genetic and genomic data and provides access to this data to support research using the rat as a genetic model for the study of human disease
Rat Candidate SNP Database, Cuppen Group(http://cascad.niob.knaw.nl/)
Investigates genetic variation (single nucleotide polymorphisms/SNPs) in relation to biological (functional) consequences and transcriptional regulatory networks
Rat Resource and Research Center(http://www.nrrrc.missouri.edu/)
Establishes a center for distributing high quality, well characterized inbred, hybrid and mutant rats to investigators
National Bio-resource Project for the Rat in Japan(http://www.anim.med.kyoto-u.ac.jp/NBR/)
Facilitates the availability of genetically and phenotypically standardized rat strains for experimental research
Biome Rat Resources(http://bioresearch.ac.uk/browse/mesh/C0034693L0034693.html)
Provides information on rat genetic and genomic activities and resources, which includes rat databases, genomic tools, courses and scientific meetings, reports and publications, and funding opportunities.
The Institute for Genome Research(http://www.tigr.org/)
Structural, functional and comparative analysis of genomes and gene products from a wide variety of organisms
NCBI, National Center for Bioinformatics Information(http://www.ncbi.nlm.nih.gov/)
NCBI creates public databases, conducts research in computational biology, develops software tools for analyzing genome data, and disseminates biomedical information
Rat Genome, EnsEMBL(http://www.ensembl.org/Rattus_norvegicus/)
The Rat Genome project is an international collaboration to sequence the genome of the brown rat (Rattus norvegicus)
Mouse Genome, EnsEMBL(http://www.ensembl.org/Mus_musculus/)
The Mouse Genome Sequencing Consortium is a joint project to provide the Mouse genome sequence to the world.
Toxicogenomics Databases
CEBS, Chemical Effects in Biological Systems(http://www.niehs.nih.gov/research/resources/databases/cebs/index.cfm)
Knowledge base for genomic, proteomic and metabonomic studies on chemicals
ArrayTrack, NCTR(http://www.fda.gov/nctr/science/centers/toxicoinformatics/ArrayTrack/index.htm)
ArrayTrack is an integrated software system for managing, mining, and visualizing microarray gene expression data
HESI Committee for the Application of Genomics to Risk Assessment(http://hesi.ilsi.org/index.cfm?pubentityid=120)
An effort to develop a collaborative scientific program to address issues, challenges and opportunities afforded by the emerging field of toxicogenomics.
MGED, Microarray Gene Expression Data(http://www.mged.org/)
The Microarray Gene Expression Data (MGED) Society aims to facilitate the sharing of microarray data generated by functional genomics and proteomics experiments
PSI, Protein Standards Initiative(http://psidev.sf.net/)
The HUPO Proteomics Standards Initiative (PSI) defines community standards for data representation in proteomics to facilitate data comparision, exchange and verification
Pathology Ontology, European Mutant Mouse(http://eulep.anat.cam.ac.uk/Pathology_Ontology/index.php)
Provide a searchable database of histopathology images derived from genetically manipulated mice
SNOMED, Systematized Nomenclature of Medicine(http://www.snomed.org/)
A division of the College of American Pathologists, focusing on patient care through the delivery of SNOMED and terminology and implementation support products and services
Mouse Phenome Database(http://aretha.jax.org/pub-cgi/phenome/mpdcgi?rtn=docs/home)
A collection of phenotypic and genotypic data for the laboratory mouse.
MGED MAGE Ontology(http://mged.sourceforge.net/ontologies/index.php)
Developing an ontology for describing samples used in microarray experiments
Ontology Review(http://mged.sourceforge.net/ontologies/MKreview.html)
Review of the clinical vocabularies
SOFG Mouse Ontology Resources(http://www.sofg.org/resources/mouse.html)
Standards and Ontologies for Functional Genomics (for mouse)
Toxicology Data
National Toxicology Program(http://ntp.niehs.nih.gov/)
Database for NTP Testing Information and Study Results
Endocrine Disruptor Knowledge Base (EDKB)(http://edkb.fda.gov/)
Biological activity database, relevant literature citations, computational models, and ultimately, models for risk assessment
ToxNet(http://toxnet.nlm.nih.gov/)
Cluster of databases on toxicology, hazardous chemicals, and related areas
DSSTox-Distributed Structure-Searchable Toxicity(http://www.epa.gov/nheerl/dsstox/)
Community forum for publishing standard format, structure-annotated chemical toxicity data files for open public access.
Homologene, NCBI(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=homologene)
System for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes
Cross Species Anatomy Network, XSPAN(http://www.aiai.ed.ac.uk/project/xspan/)
Support cross-species access to tissue-based genetic information through the development of an internet-based cross-species anatomy network.
Genetics, Pharmacogenetics
PharmGKB Knowledgebase(http://www.pharmgkb.org/index.jsp)
Integrated resource about how variation in human genes leads to variation in our response to drugs
Environmental Genomics Project(http://www.niehs.nih.gov/research/supported/programs/egp/index.cfm)
Improve understanding of human genetic susceptibility to environmental exposures
Standards and Ontologies for Functional Genomics, SOFG(http://www.sofg.org/)
Provides a community resource for the development of ontologies and other controlled vocabularies relevant to biology and biological experimentation
Systems Biology, PNNL(http://www.sysbio.org/)
Provides advanced capabilities in systems biology research
NCT Microarray Group(http://www.niehs.nih.gov/research/atniehs/core/mg/index.cfm)
description of the technology as it exists at the NIEHS, how microarray technology can be applied to studies in environmental health, some sample data
Additional Links
Unified Medical Language System(http://www.nlm.nih.gov/research/umls/)
Develops and distributes multi-purpose, electronic Knowledge Sources and associated lexical programs for system developers
BioMart(http://www.ebi.ac.uk/biomart)
A simple, distributed data integration system with powerful query capabilities
Bioconductor(http://www.bioconductor.org/)
Open source and open development software project to provide tools for the analysis and comprehension of genomic data (bioinformatics)
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