Publications

CEBS Development Forum

Waters, M.D., et al. Systems toxicology and the chemical effects in biological systems knowledge base. Environmental Health Perspectives 111, 811-824 (2003). [A detailed discussion of the concepts behind CEBS and its goals]. PMID: 12735106(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12735106)

Mattes, W.B., et al. Database development in toxicogenomics: issues and efforts. Environmental Health Perspectives 112, 495-505 (2004). [An ILSI-HESI status report on toxicogenomics-relevant databases, including CEBS]. PMID: 15033600(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15033600)

Waters, M.D. and Fostel, J.M. Toxicogenomics and systems toxicology: aims and prospects. Nature Reviews Genetics 5, 936-48 (2004). [A review on toxicogenomics that defines the role of CEBS in the field]. PMID: 15573125(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15573125)

Xirasagar, S. et al. CEBS object model for systems biology data, SysBio-OM. Bioinformatics 20, 2004-15 (2004). [A technical description of the CEBS 'omics object model for 'omics data integration PMID: 15044233(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15573125)

Sansone S-A, et al., Standardization initiatives in the (eco) toxicogenomics domain: a review. Comparative and Functional Genomics 5, 633-641 (2005). [A review of current standards for toxicogenomics].

Fostel, J., et al., Chemical effects in biological systems - data dictionary (CEBS-DD). A compendium of terms for the capture and integration of biological study design description, conventional phenotypes and 'omics data. Toxicological Sciences 88(2) 585-601 (2006) [A description of the CEBS study design, toxicology/pathology and other metadata elements]. PMID: 16150882(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16150882)

Xirasagar, S. et al., CEBS Object Model for Toxicology Data, SysTox-OM, Design, Implementation, and Application. Bioinformatics 22(7) 874-82 (2006) [A technical description of the CEBS toxicology/pathology object model]. PMID: 16410321(http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16410321)