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Your Environment. Your Health.

Brian Sayers, Ph.D.

Systems Toxicology Group

Brian Sayers
Brian C. Sayers, Ph.D.
Fellow – IRTA
Tel (919) 541-7561
P.O. Box 12233
Mail Drop K2-12
Research Triangle Park, NC 27709

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Brian Sayers, Ph.D., is an Intramural Research Training Award Fellow in the Toxicology Branch of the Division of National Toxicology Program (NTP) at the National Institute of Environmental Health Sciences.

As a trainee, Sayers serves as the study scientist for chemicals nominated to the NTP for toxicity and carcinogenicity evaluation. Currently he is the lead on studies evaluating nanomaterials, metals, volatile organic compounds (VOCs) and dietary supplements. He has a background in nanotoxicology and a particular interest in respiratory/inhalation toxicology.

Sayers received a B.S. in Toxicology from Northeastern University, Boston, Massachusetts and a Ph.D. in Toxicology from North Carolina State University, Raleigh, North Carolina. Prior to attending graduate school, he worked in the drug safety evaluation department at Sanofi-Aventis. He joined the NTP in 2013.

Selected Publications

  1. Glista-Baker EE, Taylor AJ, Sayers BC, Thompson EA, Bonner JC. Nickel Nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet). Particle and Fibre Toxicology 2014, 11(7): 1-16.[Abstract]
  2. Sayers BC, Taylor AJ, Glista-Baker EE, Shipley-Phillips JK, Dackor RT, Edin ML, Lih FB, Tomer KB, Zeldin DC, Langenbach R, Bonner JC. Role of Cyclooxygenase-2 in Exacerbation of Allergen-Induced Airway Remodeling by Multiwalled Carbon Nanotubes. American Journal of Respiratory Cell and Molecular Biology 2013, 49(4): 525-535.[Abstract]
  3. Thompson EA, Sayers BC, Glista-Baker EE, Shipkowski KA, Taylor AJ, Bonner JC. Innate Immune Responses to Nanoparticle Exposure in the Lung. Journal of Environmental Immunology and Toxicology 2013, 1(3): 150-156.
  4. Lee JK, Sayers BC, Chun KS, Lao HC, Shipley-Phillips JK, Bonner JC, Langenbach R. Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP Kinase-dependent and-independent mechanisms in mouse RAW264.7 macrophages. Particle and Fibre Toxicology 2012, 9(14):1-11.[Abstract]
  5. Glista-Baker EE, Taylor AJ, Sayers BC, Thompson EA, Bonner JC. Nickel Nanoparticles Enhance Platelet-Derived Growth Factor–Induced Chemokine Expression by Mesothelial Cells via Prolonged Mitogen-Activated Protein Kinase Activation. American Journal of Respiratory Cell and Molecular Biology 2012, 47(4): 552-561.[Abstract]

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