Rachel Patterson, M.S., is a biologist in the Toxicology Operations Branch of the Environmental Toxicology Program at the National Institute of Environmental Health Science (NIEHS), one of the National Institutes of Health. Following graduation from Clemson University, she joined NIEHS, where she performed molecular and cellular research, focusing on human and environmental health issues from 1982-2006.
She received a B.S. in biology from Christian Brothers College in 1979 and an M.S. in microbiology from Clemson University in 1982. She joined NIEHS in 1982.
Patterson is currently involved in several efforts for the National Toxicology Program (NTP).
Provides specialized scientific support coordinating toxicogenomics studies to evaluate xenobiotic-induced immunotoxicity
Assists the NTP toxicogenomics chair and supports the toxicogenomics faculty as secretary to the group
Active participant in the NIEHS educational outreach efforts
Selected Publications
Rachel Patterson and Dori Germolec. Gene Expression Alterations in Immune System Pathways Following Exposure to Immunosuppressive Chemicals. In Living in a Chemical World: Framing the Future in Light of the Past Myron A Mehlmman, Morando Soffritti, Philip Landrigan, Eula Bingham, Fiorella Belpoggi, eds. Annals of the New York Academy of Science, vol 1076, 2006.
Rachel Patterson, Kevin Trouba, and Dori Germolec. Immunotoxicology and Inflammatory Mechanisms of Arsenic. In Immunotoxicology and Immunopharmacology, Third Edition, Taylor and Francis Group, LLC. Scheduled for publication in Dec. 2006.
Rachel Patterson and Dori Germolec. Toxic Oil Syndrome: Review of the Immune Aspects of the Disease. Journal of Immunotoxicology 2:51-58, 2005.
Rachel M. Patterson, Libia Vega-Lloyo, Kevin Trouba, Carl Bortner, and Dori Germolec.
Arsenic-Induced Alterations in Contact Hypersensitivity Response in Balb/c Mice. Toxicology and Applied Pharmacology 198(3):434-443, 2004.
Rachel M. Patterson, Robert Stachlewitz, Dori Germolec
Induction of Apoptosis by 2,3,7,8-Tetrachlorodibenzo-p-dioxin Following Endotoxin Exposure. Toxicology and Applied Pharmacology 190(2):120-134, 2003.
Rachel M. Patterson, Chaoying He, James K. Selkirk, B. Alex Merrick.
Human p53 Expressed In Baculovirus-Infected Sf9 Cells Displays A Two-Dimensional Isoform Pattern Identical to Wild-Type p53 From Human Cells. Archives of Biochemistry and Biophysics 330(1):71-79, 1996.
Rachel M. Patterson, James K. Selkirk, B. Alex Merrick.
Baculovirus and Insect Cell Gene Expression: Review of Baculovirus Biotechnology. Environmental Health Perspectives 103(7-8):756-759, 1995.
Rachel M. Patterson, Lora L. Witcher, Chaoying He, James K. Selkirk, B. Alex Merrick.
Improved Protein Detection With a PVDF Transfer Membrane For Two-Dimensional Electrophoresis. Biotechniques 14(5):752-753, 1993.
Kevin Trouba, Abraham Nyska, Mirec Styblo, D. Dunson, L. Lomnitski, S. Grossman, Glinda Moser, A. Suttie, Rachel Patterson, F. Walton, and Dori Germolec. Effect of Antioxidants on the Papilloma Response and Liver Glutathione Modulation Mediated by Arsenic in Tg.AC Transgenic Mice. In Arsenic Exposure and Health Effects V Willard Chappell, Charles Abernathy, Rebecca Calderon, and David Thomas, eds. Elsevier, Boston, 2003, p 283-293.
Libia Vega, Myric Styblo, Rachel Patterson, W Cullen, C Wang, Dori Germolec.
Differential Effects Of Trivalent and Pentavalent Arsenicals On Cell Proliferation And Cytokine Secretion In Normal Human Epidermal Keratinocytes. Toxicology and Applied Pharmacology 172(3):225-232, 2001.
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