P.O. Box 12233
Mail Drop K2-06
Research Triangle Park, North Carolina 27709 Delivery Instructions
Matthew Stout, Ph.D., is a toxicologist and serves as a project officer in the administration and monitoring of contracts for NTP toxicology and carcinogenicity studies. Stout is involved in the design, conduct, interpretation, and reporting of NTP research and testing activities that investigate the toxicology, carcinogenicity and mode of action of environmental substances in rodent models. He also serves as a project leader for a diverse array of NTP chemicals, including metals, herbals, industrial compounds, flame retardants, and compounds selected to understand the mechanistic link between peroxisome proliferation and hepatocarcinogenicity. The data generated from these studies serve as a resource to state and federal regulatory agencies for predicting potential health effects in humans.
Stout received a B.S. in biochemistry from North Carolina State University and a Ph.D. in toxicology from the University of North Carolina at Chapel Hill. He was an NIEHS postdoctoral intramural research and training award (IRTA) fellow in applied toxicology and carcinogenesis in the NTP Toxicology Branch.
Selected Publications
Stout MD, Herbert RA, Kissling GE, Collins BJ, Travlos GS, Witt KL, Melnick RL, Abdo KM, Malarkey DE, and Hooth MJ (2009) Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure. Environ. Health Perspect, 117, 716-722. [Abstract](http://www.ncbi.nlm.nih.gov/pubmed/19479012?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Stout MD, Nyska A, Collins BJ, Witt KL, Kissling GE, Malarkey DE, and Hooth MJ (2009) Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years. Food Chem. Toxicol, 47, 729-733. [Abstract](http://www.ncbi.nlm.nih.gov/pubmed/19166900?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Stout MD, Kissling GE, Suárez FA, Malarkey DE, Herbert RA, and Bucher JR (2008) Influence of Helicobacter hepaticus infection on the chronic toxicity and carcinogenicity of triethanolamine in B6C3F1 mice. Toxicol. Pathol, 36, 783-794.[Abstract](http://www.ncbi.nlm.nih.gov/pubmed/18812577?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Stout MD, Bodes E, Schoonhoven R, Upton PB, Travlos GS, and Swenberg JA (2008) Toxicity, DNA binding and cell proliferation in male F344 rats following short-term gavage exposures to trans-2-hexenal. Toxicol. Pathol, 36, 232-246.[Abstract](http://www.ncbi.nlm.nih.gov/pubmed/18362197?ordinalpos=4&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Stout MD, Herbert RA, Kissling GE, Suarez F, Roycroft JH, Chhabra RS, and Bucher JR (2008) Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following 2-year inhalation exposure. Toxicology, 244, 209-219.[Abstract](http://www.ncbi.nlm.nih.gov/pubmed/18178301?ordinalpos=5&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Stout MD, Jeong YC, Boysen G, Li Y, Sangaiah R, Ball LM, Gold A, and Swenberg JA (2006) LC/MS/MS method for the quantitation of trans-2-hexenal-derived exocyclic 1,N2-propanodeoxyguanosine in DNA. Chem. Res. Toxicol, 19, 563-70.[Abstract](http://www.ncbi.nlm.nih.gov/pubmed/16608168?ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
|