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Selected Publications

Mammalian Aging Group

  1. Purushotham, A., Schug, T. T., Xu, Q., Surapureddi, S., Guo, X., and Li, X. (2009). Hepatocytes-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. Cell Metabolism in press.
  2. Li, X., Zhang, S., Blander, G., Tse, J.G., Krieger, M., and Guarente, L. (2007). SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Molecular Cell. 28:91-106.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17936707?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DiscoveryPanel.Pubmed_RVAbstractPlus) Exit NIEHS
  3. Li, X., and Gould, S.J. (2003). The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11. J. Biol. Chem. 278:17012-12020.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12618434) Exit NIEHS
  4. Li, X., Baumgart, E., Dong, G.-X., Morrell, J.C., Jimenez-Sanchez, G., Valle, D., Smith, K.D., and Gould, S.J. (2002). PEX11a is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for PPARa-mediated peroxisome proliferation. Mol. Cell. Biol. 22:8226-8240.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12417726) Exit NIEHS
  5. Li, X., Baumgart, E., Morrell, J., Jimenez-Sanchez, G., Valle, D., and Gould, S.J. (2002). PEX11ß-deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function. Mol. Cell. Biol. 22: 4358-4365.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12024045) Exit NIEHS
  6. Li, X., and Gould, S.J. (2002). PEX11 promotes peroxisome division independently of peroxisome metabolism. J. Cell. Biol. 156:643-651.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11839773) Exit NIEHS
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Last Reviewed: March 23, 2009