Structural Biology Laboratory
Core Facilities and Research Support Groups
The Laboratory of Structural Biology maintains the following core facilities and research support groups at NIEHS.
- Protein Expression Core Facility
The Protein Expression Core Facility assists NIEHS investigators with their protein expression requirements. The facility is located in Room F-145. Robert M. Petrovich, Ph.D., heads the facility.
- Protein Microcharacterization Core Facility
The Protein Microcharacterization Core Facility supports intramural research projects through cutting-edge mass spectrometry services, including protein identification and characterization of post-translational protein modifications. The facility is located in room F-012. Jason Williams, Ph.D., heads the facility.
- Collaborative X-ray Crystallography Group. This support group contains instruments necessary for structural determinations using x-ray crystallography. Investigators with the necessary expertise may access this equipment for their own research. It is located on the third floor of the F module in Building 101. Lars Pedersen, Ph.D., heads the group.
- Computational Chemistry/Molecular Modeling Support Group. This support group assists investigators with structural alignments, docking, modeling, energetics, and graphics visualizations. It is headed by Lalith Perera, Ph.D.
- Collaborative Mass Spectrometry Support Group. This support function specializes in characterizing proteins, quantifying changes in protein abundance in cells and animals upon exposure to external factors, and identifying and quantifying small molecules. It is headed by Leesa Deterding, Ph.D.