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Selected Publications

Mass Spectrometry Group

  1. Cheng J, Edin ML, Hoopes SL, Li H, Bradbury JA, Graves JP, DeGraff LM, Lih FB, Garcia V, Shaik JS, Tomer KB, Flake GP, Falck JR, Lee CR, Poloyac SM, Schwartzman ML, Zeldin DC. Vascular characterization of mice with endothelial expression of cytochrome P450 4F2. FASEB journal: official publication of the Federation of American Societies for Experimental Biology 2014 28(7):2915-2931.[Abstract ]
  2. Mueller GA, Makeli SJ, Johnson K, Hurlburt BK, Cheng H, Ruan S, Nesbit JB, Pomés A, Edwards LL, Schorzman A, Deterding LJ, Park H, Tomer KB, London RE, Williams JG. Identification of Maillard reaction products on peanut allergens that influence binding to the receptor for advanced glycation end products. Allergy 2013 68(12):1546-1554.[Abstract ]
  3. Mueller GA, Pedersen LC, Lih FB, Glesner J, Moon AF, Chapman MD, Tomer KB, London RE, Pomés A. The novel structure of the cockroach allergen Bla g 1 has implications for allergenicity and exposure assessment. Journal of Allergy and Clinical Immunology 2013 132(6):1420-1426.[Abstract ]
  4. Perdivara I, Perera L, Sricholpech M, Terajima M, Pleshko N, Yamauchi M, Tomer KB. Unusual fragmentation pathways in collagen glycopeptides. Journal of the American Society for Mass Spectrometry 24(7):1072-1081, 2013. [Abstract ]
  5. Dhungana S, Merrick BA, Tomer KB, Fessler MB. Quantitative proteomics analysis of macrophage rafts reveals compartmentalized activation of the proteasome and of proteasome-mediated ERK activation in response to lipopolysaccharide. Molecular & Cellular Proteomics: MCP 8(1):201-213, 2013.[Abstract ]
  6. Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnes CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D'Amore PA, Kieran MW , Zeldin DC. Epoxy-eicosanoids stimulate multi-organ metastasi and tumor dormancy escape in mice. The Journal of clinical investigation 122(1):178-91, 2012.[Abstract ]
  7. Sricholpech M, Perdivara I, Yokoyama M, Nagaoka H, Terajima M, Tomer KB, Yamauchi M. Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. The Journal of biological chemistry 2012 287(27):22998-3009.[Abstract ]
  8. Merrick B.A., Dhungana S., Williams J.G., Aloor J.J., Peddada S., Tomer K.B., Fessler M.B. Proteomic profiling of S-acylated macrophage proteins identifies a role for palmitoylation in mitochondrial targeting of phospholipid scramblase 3. Molecular & Cellular Proteomics: MCP 10(10):M110.006, 2011.[Abstract ]
  9. Bhattacharjee, S., Deterding, L.J., Chatterjee, S., Jiang, J.J., Ehrenshaft, M., Lardinois, O., Ramirez, D.C., Tomer, K.B., Mason, R.P. Site-specific radical formation in DNA induced by Cu(II)-H2O2 oxidizing system, using ESR, Immuno-spin trapping, LC-MS and MS/MS. Free radical biology & medicine, 50(11):1536-1545, 2011.[Abstract ]
  10. Perdivara, I., Peddada, S.D., Miller, F.W. , Tomer, K.B., Deterding, L.J. Mass spectrometric determination of IgG subclass-specific glycosylation profiles in siblings discordant for myositis syndromes. Journal of proteome research, 10(7):2969-2978, 2011.[Abstract ]
  11. Schorzman AN, Perera L, Cutalo-Patterson JM, Pedersen LC, Pedersen LG, Kunkel TA, Tomer KB. Modeling of the DNA-binding site of yeast Pms1 by mass spectrometry. DNA repair, 10(5):454-465, 2011.[Abstract ]
  12. Sricholpech, M., I. Perdivara, H. Nagaoka, M. Yokoyama, K.B. Tomer, M. Yamauchi. Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in Type 1 collagen in osteoblasts culture. The Journal of biological chemistry, 286(11):8846-8856, 2011.[Abstract ]
  13. Deterding, L.J., J.S. Williams, M.M. Humble, R.M. Petrovich, S.J. Wei, C.S. Trempus, M.B. Gates, F. Zhu, R.C. Smart, R.W. Tennant, K.B. Tomer. CD34 Antigen: Determination of Specific Sites of Phosphorylation In Vitro and In Vivo. International journal of mass spectrometry, 301(1-3):12-21, 2011.[Abstract ]
  14. Deng, Y., M.L. Edin, K.N. Theken, R.N. Schuck, G.P. Flake, M.A. Kannon, L.M. DeGraff, F.B. Lih, J. Foley, J.A. Bradbury, J.P. Graves, K.B. Tomer, J.R. Falck, D.C. Zeldin, C.R. Lee. Endothelial CYP epoxygenase overexpression and soluble epoxide hydrolase disruption attenuate acute vascular inflammatory responses in mice. The FASEB journal, 25(2):703-713, 2011.[Abstract ]
  15. Chatterjee, S., Lardinois, O., Bhattacharjee, S., Tucker, J., Corbet, J., Deterding. L,, Ehrenshaft, M., Bonini, M., Mason, R.P. Oxidative stress induces protein and DNA radical formation in follicular dendritic cells (FDCs) of the germinal center and modulates its cell death patterns in late sepsis. Free radical biology & medicine, 50(8):988-999, 2011.[Abstract ]
  16. Lardinois, O.M., S. Chatterjee, R.P. Mason, K.B. Tomer, L.J. Deterding. Biotinylated analogue of the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide for the detection of low-abundance protein radicals by mass spectrometry. Analytical Chemistry, 82(22):9155-9158, 2010.[Abstract ]
  17. Matsuoka, T., J.E. Adair, F.B. Lih, L.C. Hsi, M. Rubino, T.E. Eling, K.B. Tomer, M. Yashiro, K. Hirakawa, K. Olden, J.D. Roberts. Elevated dietary linoleic acid increases gastric carcinoma cell invasion and metastasis in mice. British journal of cancer, 103(8):1182-1191, 2010.[Abstract ]
  18. Lee, C.R., J.D. Imig, M.L. Edin, J. Foley, L.M. DeGraff, J.A. Bradbury, J.P. Graves, F.B. Lih, J. Clark, P. Myers, L. Perrow, A.N. Lepp, M.A. Kannon, O.K. Ronnekleiv, N.J. Alkayed, J.R. Falck, K.B. Tomer, D.C Zeldin. Endothelial expression of human cytochrome P450 epoxygenases lowers blood pressure and attenuates hypertension-induced renal injury in mice. The FASEB journal, 24(10):3770-3781, 2010.[Abstract ]
  19. Lih, F.B., M.A. Titus, J.L. Mohler, K.B. Tomer. Atmospheric pressure photoionization tandem mass spectrometry of androgens in prostate cancer. Analytical Chemistry, 82(14):6000-6007, 2010.[Abstract ]
  20. Perdivara, I., L.J. Deterding, M. Przybylski, K.B. Tomer. Mass spectrometric identification of oxidative modifications of tryptophan residues in proteins: chemical artifact or post-translational modifications?. Journal of The American Society for Mass Spectrometry, 21(7):1114-1117, 2010.[Abstract ]
  21. Konno, Y., H. Kamino, R. Moore, F. Lih, K.B. Tomer, D.C. Zeldin, J.A. Goldstein, M. Negishi. The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver. Drug Metabolism and Disposition, 38(7):1177-1182, 2010.[Abstract ]
  22. Perdivara, I., J. Deterding, C. Cozma, K.B. Tomer, M. Przybylski. Glycosylation profiles of epitope-specific anti-beta-amyloid antibodies revealed by liquid chromatography-mass spectrometry. Glycobiology, 19(9):958-970, 2009.[Abstract ]
  23. Chatterjee, S., O.M. Lardinois, M.G., Bonini, S. Bhattacharjee, K. Stadler, J. Corbett, L.G. Deterding, K.B. Tomer, M. Kadiiska, R.P. Mason. Site-specific CPB1 tyrosine nitration and its patho-physiological implications following coupling with NOS-3 in experimental sepsis. Journal of immunology, Baltimore, Md., 183(6):4055-4066, 2009.[Abstract ]
  24. Lardinois, O.M., D.A. Maltby, K.F. Medzihradszky, P.R. Ortiz de Montellano, K.B. Tomer, R.P. Mason, L.J. Deterding. Spin Scavenging Analysis of Myoglobin Protein-Centered Radicals Using Stable Nitroxide Radicals: Characterization of Oxoammonium Cation-Induced Modifications. Chemical Research in Toxicology, 22(6):1034-1049, 2009.[Abstract ]
  25. Chatterjee, S., M. Ehrenshaft, S. Bhattacharjee, L.J. Deterding, M.G. Bonini, J. Corbett, M. Kadiiska, K.B. Tomer, R.P. Mason. Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. Free radical biology & medicine, 46(4):454-461, 2009.[Abstract ]
  26. Ye, W., R. Sangaiah, D.E. Degen, A. Gold, K. Jayaraj, K.M. Koshlap, B. Boysen, J. Williams, K.B. Tomer, V. Mocanu, N. Dicheva, C. Parker, R.M. Schaaper, L.M. Ball. Iminohydantoin lesion induced in DNA by peracids and other epoxidizing oxidants. Journal of the American Chemical Society, 131(17):6114-6123, 2009.[Abstract ]
  27. Ehrenshaft, M., S. de Oliveira Silva, I. Perdivara, P. Bilski, R.H. Sik, C.F. Chignell, K.B. Tomer, R.P. Mason. Immunological detection of N-formylkynurenine in oxidized proteins. Free radical biology & medicine, 46(9):1260-1266, 2009.[Abstract ]
  28. Perdivara, I., R. Petrovich, B. Alliquant, L.J. Deterding, K.B. Tomer, M. Przybylski. Elucidation of O-glycosylation structures of the ß-amyloid precursor protein by liquid chromatography - mass spectrometry using electron transfer dissociation and collision induced dissociation. Journal of proteome research, 8(2):631-642, 2009.[Abstract ]
  29. Chattopadhyay, R., R. Iacob, S. Sen, R. Majumder, K.B. Tomer, B.R. Lentz. Functional and structural characterization of factor Xa dimer in solution. Biophysical journal, 96(3):974-986, 2009.[Abstract ]
  30. Vitorino, R., S. Guedes, K.B. Tomer, P. Domingues, J. Duarte, F. Amado. On-plate digestion using a commercial microfraction collector for nano-HPLC matrix-assisted laser desorption/ionization tandem time-of-flight protein analysis. Analytical biochemistry, 380(1):128-130, 2008.[Abstract ]
  31. Smedley III, J.G., J.S. Sharp, J.F. Kuhn, K.B. Tomer. Probing the pH-dependent prepore to pore transition of Bacillus anthracis protective antigen with differential oxidative protein footprinting. Biochemistry, 47(40):10694-10704, 2008.[Abstract ]
  32. McEntee, M.F., C. Ziegler, D. Reel, K.B. Tomer, A. Shoieb, M. Raym, X. Li, N. Neilsen, F.B. Lih, D. O'Rourke, J. Whelan. Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer. The American journal of pathology, 173(1):229-241, 2008.[Abstract ]
  33. Deterding, L.J., B.K. Bunger, G.C. Banks, K.B. Tomer, T.K. Archer. Global changes in and characterization of specific sites of phosphorylation in mouse and human histone H1 Isoforms upon CDK inhibitor treatment using mass spectrometry. J Proteome Res., 7:2368-2379, 2008.[Abstract ]
  34. McEntee, M.F., C. Ziegler, D. Reel, K.B. Tomer, A. Shoieb, M. Ray, X. Li, N. Neilsen, F.B. Lih, D. O'Rourke, J. Whelan. Dietary n-3 polyunsaturated fatty acids enhance hormone ablation therapy in androgen-dependent prostate cancer. Am. J. Pathol., 173:229-241, 2008.[Abstract ]
  35. Siraki, A., L.J. Deterding, M. Bonini, J.J. Jiang, M. Ehrenshaft, K.B. Tomer, R.P. Mason. Procainamide, but not N-acetylprocainamide, induces protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. Chem. Res. Toxicol., 21:1143-1153, 2008.  [Abstract ]
  36. Deterding, L.J., M.K. Bunger, G.C. Banks, K.B. Tomer, T.K. Archer. Global changes in and characterization of specific sites of phosphorylation in mouse and human histone h1 isoforms upon CDK inhibitor treatment using mass spectrometry. J. Proteome Res., 7:2368-2379, 2008.[Abstract ]
  37. Iacob, R.E., Z. Keck, O. Olson, S.K. Foung, K.B. Tomer. Structural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 glycoprotein. Biochim. Biophys. Acta-Proteins and Proteomics, 1784(3):530-542, 2008.[Abstract ]
  38. Iacob, R.E., I. Perdivara, M. Przybylski, K.B. Tomer. Mass spectrometric characterization of glycosylation of Hepatitis C virus E2 envelope glycoprotein reveals extended microheterogeneity of N-glycans. J. Amer. Soc. Mass Spectrom., 19:428-444, 2008.[Abstract ]
  39. Lardinois, O.M., C.D. Detweiler, K.B. Tomer, R.P. Mason, L.J. Deterding. Identifying the site of spin-trapping in proteins by a combination of liquid chromatography, ELISA and off-line tandem mass spectrometry. Free Rad. Biol & Med., 44:893-906, 2008.[Abstract ]
  40. Fostel, J., M. Waters, S. Stasiewicz, B.A. Merrick, K.B. Tomer, P. Bushel, R. Paules, N. Stegman, K. Yost, C. Johnson, S. Gustafson, S. Xirasagar, N. Xiao, C.-C. Huang, P. Boyer, D. Chan, Q. Pan, H. Gong, J. Taylor, D. Choi. CEBS: Chemical effects in biological systems. A public data repository integrating study design and toxicity data with microarray and proteomics data. Nuc. Acid Res., 36:D892-D900, 2008.[Abstract ]
  41. Cuthbertson, B.J., L.J. Deterding, J.G. Williams, K.B. Tomer,, K. Etienne, P.J. Blackshear, E.E. Büllesbach, P.S. Gross. Diversity in penaeidin antimicrobial peptide form and function. Devel. Comp. Immun., 32:167-181, 2008.[Abstract ]
  42. Perdivara, I., E. Sisu, I. Sisu, N. Dinca, K.B. Tomer, M. Przybylski, A.D. Zamfir. Enhanced electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry of long chain polysaccharides. Rap. Commun. Mass Spectrom., 22:773-782, 2008.[Abstract ]
  43. Perdivara, I., L.J. Deterding, A. Moise, K.B. Tomer, M. Przybylski. Determination of primary structure and microheterogeneity of a β-amyloid plaque-specific antibody using high performance LC - tandem mass spectrometry. Analytical and bioanalytical chemistry 391(1):325-336, 2008.[Abstract ]
  44. Bhattacharjee, S., Deterding L.J., Jiang J.J., Bonini M.G., Tomer K.B., Ramirez D.C., Mason RP. Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. Journal of the American Chemical Society 129(44):13493-13501, 2007.[Abstract ]
  45. Deterding, L.J., S. Bhattacharjee, D.C. Rameriz, R.P. Mason, K.B. Tomer. Top-down and bottom-up mass spectrometric characterization of human myoglobin-centered free radicals induced by oxidative damage. Analytical chemistry 79(16):6236-6248, 2007.[Abstract ]
  46. Sharp, J.S., K.B. Tomer. Analysis of the oxidative damage-induced conformational changes of Apo- and Holo-calmodulin by dose-dependent protein oxidative surface mapping. Biophys. J., 92(5):1682-1692, 2007.[Abstract ]
  47. Cutalo, J.M., T.A. Darden, T.A. Kunkel, K.B. Tomer. Mapping the dimer interface in the C-terminal domains of the yeast MLH1-PMS1 heterodimer. Biochemistry, 45(51): 15458-15467, 2006. [Abstract ]
  48. Williams, J.G., C.E. Hioe, S. Zolla-Pazner, P.J. Norris, K.B. Tomer. The Antigenic Determinants on HIV p24 for CD4+ T Cell Inhibiting Antibodies as Determined by Limited Proteolysis, Chemical Modification, and Mass Spectrometry. J. Am. Soc. Mass Spectrom., 17:1560-1569, 2006. [Abstract ]
  49. Sharp, J.S., K.B. Tomer. Effects of anion proximity in peptide primary sequence on the rate and mechanism of leucine oxidation. Anal. Chem. 78:4885-4893, 2006.[Abstract ]
  50. Merrick, B.A., M.E. Bruno, J.H. Madenspacher, B.A. Wetmore, J. Foley, R. Pieper, M. Zhao, A.J. Makusky, A.M. McGrath, J.X. Zhou, J. Taylor, K.B. Tomer. Alterations in the rat serum proteome during liver injury from acetaminophen exposure. J. Pharm. Exp. Thera., 318:792-802, 2006.[Abstract ]
  51. Sharp, J.S., D.M. Sullivan, J. Cavanagh, K.B. Tomer. Measurement of multi-site oxidation kinetics reveals a specific conformational change in Spo0F as a result of protein oxidation. Biochem., 45:6260-6266, 2006.[Abstract ]
  52. Hager-Braun, C., H. Katinger, K.B. Tomer. The HIV-neutralizing monoclonal antibody 4E10 recognizes N-terminal sequences on the native antigen. J. Immunol., 176:7471-7481, 2006. [Abstract ]
  53. Xirasagar, S., S.F. Gustafson, C.-C. Huang, Q. Pan, J. Fostel, P. Boyer, B.A. Merrick, K.B. Tomer, D.D. Chan, K.J. Yost III, D.Choi, N. Xiao, S. Stasiewicz, P. Bushel, M.D. Waters. Chemical Effects in Biological Systems (CEBS) Object Model for Toxicology Data, Sys-Tox-OM: Design and Application. Bioinformatics, 22:874-882, 2006. [Abstract ]
  54. Ye, W., R. Sangaiah, D.E. Degen, A. Gold, K. Jayaraj, K.M. Koshlap, G. Boyesen, J. Williams, K.B. Tomer, L.M. Ball. A 2-Iminohydantoin from the oxidation of guanine. Chem. Res. Toxicol, 19:506-510, 2006.[Abstract ]
  55. Kuhn, J., P. Hoerth, S.T. Hoehn, T. Preckel, K.B. Tomer. Proteomics study of anthrax lethal toxin-treated murine macrophages. Electrophoresis, 27:1584-1597, 2006. [Abstract ]
  56. Vitorino, R., S. Guedes, R. Ferreira, M.J.C. Lobo, J. Duarte, A.J. Ferrer-Correia, K. Tomer, P. Domingues, F.L. Amado. 2D electrophoresis study of in vitro pellicle formation and dental caries susceptibility. Eur. J. Oral Sci., 114(2):147-153, 2006.[Abstract ]
  57. Sharp, J.S., S. Nelson, D. Brown, K.B. Tomer. Structural characterization of the E2 glycoprotein from Sindbis by lysine biotinylation and LC-MS/MS. Virol., 348: 216-223, 2006.[Abstract ]
  58. Cao, H., L.J. Deterding, J.D. Venable, E.A. Kennington, J.R. Yates, III, K.B. Tomer, P.J. Blackshear. Identification of the anti-inflammatory protein tristetraprolin as a hyperphosphorylated protein by mass spectrometry and site-directed mutagenesis. Biochem. J., 394(1): 285-297, 2006.[Abstract ]
  59. Fostel, J., D. Choi, C. Zwick, N. Morrison, A. Rashid, A. Hasan, W. Bao, A. Richard, W. Tong, P.R. Bushel, R. Brown, M. Bruno, M.L. Cunningham, D. Dix, W. Eastin, C. Frade, A. Garcia, A. Heinloth, R. Irwin, J. Madenspacher, B.A. Merrick, T. Papoian, R. Paules, P. Rocca-Serra, A.-S. Sansone, J. Stevens, K. Tomer, C. Yang, M. Waters. Chemical Effects in Biological Systems – Data Dictionary (CEBS-DD): A compendium of terms for the capture and integration of biological study design description, conventional phenotypes and ‘omics’ data. Toxicol. Sci., 88(2):585-601, (Dec.)2005. [Abstract ]
  60. De Morais-Guedes, S., R. Vitorino, R. Domingues, K. Tomer, A.J. Ferrer-Correia, F. Amado, P. Domingues. Proteomics of immune-challenged Drosophila melanogaster larvae heamolymph. Biochem. Biophys. Res. Commun., 328:106-115, 2005. [Abstract ]
  61. Hartman, T.J., D.J. Baer, L.B. Graham, W.I. Stone, E.W. Gunter, C.E. Parker, P.S. Albert, J.F. Dorgan, B.A. Clevidence, W.S. Campbell, K.B. Tomer, J.T. Judd, P.R. Taylor. Moderate alcohol consumption and levels of antioxidant vitamins and isoprostanes in postmenopausal women. Eur. J. Clin. Nutrition, 59:161-8, 2005. [Abstract ]
  62. M.B. Kadiiska, B.C. Gladen, D.B. Baird, D. Germolec, L.B. Graham, C.E. Parker, A. Nyska, J.T. Wachsman, B.N. Ames, S. Basu, N. Brot, G.A. Fitzgerald, R.A. Floyd, M. George, J.W. Heinecke, G.H. Hatch, K. Hensley, J.A. Lawson, L.J. Marnett, J.D. Morrow, D.M. Murray, J. Plastaras, L.J. Roberts, J. Rokach, M.K. Shigenaga, R.S. Sohal, J. Sun, R.R. Tice, D.H. Van Thiel, D. Wellner, P.B. Walter, K.B. Tomer, R.P. Mason, J.C. Barrett. Biomarkers of Oxidative Stress Study. II. Are Oxidation Products of Lipids, Proteins and DNA Markers in CCl4 Poisoning? Free Rad. Biol. Med., 38:698-710, 2005.[Abstract ]
  63. Kadiiska, M.B., B.C. Gladen, D.B. Baird, L.B. Graham, C.E. Parker, A.B.N. Ames, S. Basu, G.A. Fitzgerald, J.A. Lawson, L.J. Marnett, D.M. Murray, J. Plastaras, L.J. Roberts, M.K. Shigenaga, J. Sun, P.B. Walter, K.B. Tomer, J.C. Barrett and R.P. Mason. Biomarkers of Oxidative Stress Study III. Effect of the Non-Steroidal Anti-inflammatory Agents Indomethacin and Meclofenamic acid on Measurements of Oxidative Products of Lipids in CCl4 Poisoning. Free Rad. Biol. Med., 38:711-718, 2005.[Abstract ]
  64. Sharp, J. S., K.B. Tomer. Formation of b(n-1) + OH + H ions by solution-phase chemistry. J. Amer. Soc. Mass Spectrom., 16:607-621, 2005. [Abstract ]
  65. Titus, M.A., M.J. Schell, F.B. Lih, K.B. Tomer, J.L. Mohler. Testosterone and dihydrotestosterone tissue levels in recurrent prostate cancer. Clin. Cancer Res., 11(13):4653-7, 2005. [Abstract ]
  66. Rhodin N.R., J.M. Cutalo, K.B. Tomer, W.P. McArthur, L.J. Brady. Characterization of the Streptococcus mutans P1 epitope recognized by immunomodulatory monoclonal antibody 6-11A. Infect. Immun., 72:4680-8, 2004.[Abstract ]
  67. Detweiler, C.D., O.M. Lardinois, L.J. Deterding, P.O. de Montellano, K. B. Tomer, R.P. Mason. Identification of the Myoglobin Tyrosyl Radical by Immuno-spin Trapping and its Dimerization. Free Radi. Biol. Med., 38:969-976, 2005.[Abstract ]
  68. Cutalo, J.M., L.J. Deterding, K.B. Tomer. Characterization of Glycopeptides From HIV-ISF2 gp120 by Liquid Chromatography Mass Spectrometry. J. Amer. Soc. Mass Spectrom., 15(11):1545-1555, 2004.[Abstract ]
  69. Williams, J., K.B. Tomer. Disposable Chromatography for a High-throughput Nano-ESI/MS and Nano-ESI/MS-MS Platform. J. Amer. Soc. Mass Spectrom., 15:1333-1340, 2004.[Abstract ]
  70. Vitorino, R., M.J.C. Lobo, A.J. Ferrer-Correia, K.B. Tomer, P.M. Domingues, F.M.L. Amado. In vitro hydroxyapatite adsorbed salivary proteins. Biochem. Biophys. Res. Commun., 320:342-346, 2004. [Abstract ]
  71. Xirasagar, S., S. Gustafson, A. Merrick, K.B. Tomer, S. Stasiewicz, D.D. Chan, K.J. Yost III, J.R. Yates III, S. Sumner, N. Xiao, M.D. Waters. CEBS Object Model for Systems Biology Data, SysBio-OM. Bioinformatics, 20:2004-2015, 2004.[Abstract ]
  72. Deterding, L.J., D.C. Ramirez, J.R. Dubin, R.P. Mason, K.B. Tomer. Identification of free radicals on hemoglobin from its self-peroxidation using mass spectrometry and immuno-spin trapping: observation of a histidinyl radical. J. Biol. Chem., 279:11600-11607, 2004.[Abstract ]
  73. Vitorino R, M.J.C. Lobo, P. Domingues, A.J. Correia, K.B. Tomer, F.M.L. Amado. Analysis of Salivary peptides using HPLC-Electrospray Mass Spectrometry. Biomedical Chromatography 18(8):570-5, 2004.[Abstract ]
  74. Vitorino, R., M.J.C. Lobo, A.J. Ferrer-Correia, J.R. Dubin, K.B. Tomer, P.M. Domingues, F.M.L. Amado. Identification of human whole saliva protein components using proteomics. Proteomics, 4(4):1109-1115, 2004.[Abstract ]
  75. De Morais-Guedes, S., R. Vitorino, K.B. Tomer, R.M. Domingues, A.J. Ferrer-Correia, F. Amado, P. Domingues. Drosophila melanogaster larval heamolymph protein mapping. Biochem. Biophys. Res. Commun., 312:545-554, 2003.[Abstract ]
  76. Deterding, L.J., M. Khaledi, K.B. Tomer. Effect of nonaqueous buffer modifiers on the capillary electrophoresis/mass spectrometry analysis of peptides. J. Capillary Electrophoresis, 8(1/2):11-18, 2003.[Abstract ]
  77. Hall, M.C., P. Shcherbakova, J.M. Fortune, C.H. Borchers, J.M. Dial, K.B. Tomer, T.A. Kunkel. DNA binding by yeast Mlh1 and Pms1: Implications for DNA mismatch repair. Nucleic Acids Res. 31(8):2025-2034, 2003.[Abstract ]
  78. Iida, M., C.H. Anna, J. Hartis, M. Bruno, B. Wetmore, J.R. Dubin, S. Sieber, L. Bennett, M.L. Cunningham, R.S. Paules, K.B. Tomer, C.D. Houle, B.A. Merrick, R.C. Sills, T.R. Devereux. Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens Oxazepam and Wyeth-14,643. Carcinogenesis 24:757-770, 2003. [Abstract ]
  79. Deterding, L.J., M. Khaledi, K.B. Tomer. Effect of nonaqueous buffer modifiers on the capillary electrophoresis/mass spectrometry analysis of peptides. J. Capillary Electrophoresis, 8(1/2):11-18, 2003. [Abstract ]
  80. Bruno, M.E., C.H. Borchers, J.M. Dial, N.J. Walker, J.E. Hartis, B.E. Wetmore, J.C. Barrett, K.B. Tomer, B.A. Merrick. Effects of TCDD upon IkB and IKK subunits localized in microsomes by proteomics. Arch. Biochem. Biophys., 406(2):153-164, 2002.[Abstract ]
  81. Chen, Y.-R., L.J. Deterding, B.E. Sturgeon, K.B. Tomer, R.P. Mason. Protein oxidation of cytochrome c by reactive halogen species enhances its peroxidase activity. J. Biol. Chem., 77:29781-29791, 2002.[Abstract ]
  82. Qian, S.Y., K.B. Tomer, G. Yue, Q. Guo, M.B. Kadiiska, R.P. Mason. Characterization of the initial carbon-centered pentadienyl radical and subsequent radicals in lipid peroxidation: Identification via on-line high performance liquid chromatography/electron spin resonance and mass spectrometry. Free Radical Biology & Medicine, 33:998-1009, 2002. [Abstract ]
  83. Detweiler, C.D., L.J. Deterding, K.B. Tomer, C.F. Chignell, D. Germolec, R.P. Mason. Immunological identification of the heart myoglobin radical specifically formed by hydrogen peroxide. Free Radical Biology and Medicine, 33(3):364-369, 2002.[Abstract ]
  84. Qian, S.Y., Y.-R. Chen, L.J. Deterding, Y.C. Fann, C.F. Chignell, K.B. Tomer, R.P. Mason. Identification of protein-derived tyrosyl radical in the reaction of cytochrome c and hydrogen peroxide: Characterization by ESR spin-trapping, high performance liquid chromatography, and mass spectrometry. Biochem. J., 363(2):281-288, 2002. [Abstract ]
  85. Deterding, L.J., J.M. Cutalo, M. Khaledi, K.B. Tomer. Separation and characterization of human high density apolipoproteins using nonaqueous modifiers in capillary electrophoresis/mass spectrometry. Electrophoresis, 23(14):2296-2305, 2002.[Abstract ]
  86. Wine, R.N., C.E. Parker, J.M. Dial, K.B. Tomer, C.H. Borchers. Identification of components of protein complexes using a fluorescent photo-crosslinker and mass spectrometry. Anal. Chem., 74(9):1939-1945, 2002. [Abstract ]
  87. Hager-Braun, C., K.B. Tomer. Characterization of the tertiary structure of soluble CD4 bound to glycosylated full-length HIV gp120 by chemical modification of arginine residues and mass spectrometric analysis. Biochem., 41:1759-1766, 2002.[Abstract ]
  88. Guo, Q., J.T. Corbett, G. Yue, Y.C. Fann, S.Y. Qian, K.B. Tomer, R.P. Mason. Electron spin resonance investigation of semiquinone radicals formed from the reaction of ubiquinone 0 with human oxyhemoglobin. J. Biol. Chem. 277(8):6104-6110, 2002. [Abstract ]
  89. Parker, C.E., K.B. Tomer. MALDI/MS-based epitope mapping of antigens bound to immobilized antibodies. Mol. Biotechnol. 20(1):49-62, 2002.[Abstract ]
  90. Parker, C.E., L.J. Deterding, C. Hager-Braun, J.M. Binley, N. Schuelke, H. Katinger, J.P. Moore, K.B. Tomer. Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody, 2F5. J. Virol., 75:10906-10911, 2001.[Abstract ]
  91. Banks, G.C., L.J. Deterding, K.B. Tomer, T.K. Archer. Hormone mediated dephosphorylation of specific histone H1 isoforms. J. Biol Chem., 276:36467-36473, 2001. [Abstract ]
  92. Peter, J.F., K.B. Tomer. A general strategy for epitope mapping by direct MALDI-TOF mass spectrometry using secondary antibodies and crosslinking. Anal. Chem., 73:4012-4019, 2001.[Abstract ]
  93. Parker, C.E., L.B. Graham, M.-N. Nguyen, B.C. Gladen, M. Kadiiska, J.C. Barrett, K.B. Tomer. An improved GC/MS-based procedure for the quantitation of the isoprostane 15-F2t IsoP in rat plasma. Molecular Biotechnology, 18:105-118, 2001.[Abstract ]
  94. Petrotchenko, E.V., L.C. Pedersen, C.H. Borchers, K.B. Tomer, M. Negishi. The dimerization motif of cytosolic sulfotransferases. FEBS Lett., 490:39-43, 2001.[Abstract ]
  95. Tomer, K.B. Separations Combined With Mass Spectrometry. Chem. Rev., 101:297 328, 2001.[Abstract ]
  96. Merrick, B.A., W. Zhou, K.J. Martin, S. Jeyarajah, C.E. Parker, J.K. Selkirk, K.B. Tomer, C.H. Borchers. Site-specific phosphorylation of human p53 protein determined by mass spectrometry. Biochem., 40:4053-4066, 2001. [Abstract ]
  97. Deterding, L.J., J. Kast, M. Przybylski, K.B. Tomer. Molecular characterization of a tetramolecular complex between dsDNA and a DNA-binding leucine zipper peptide dimer by mass spectrometry. Bioconj. Chem., 11(3): 335-344, 2000.[Abstract ]
  98. Zhou, W., K.B. Tomer, M.G. Khaledi. Evaluation of the binding between potential anti-HIV DNA based drugs and viral envelope glycoprotein gp120 by capillary electrophoresis with laser-induced fluorescence detection. Anal. Biochem., 284(2): 334-341, 2000.[Abstract ]
  99. Zhu, X., C. Borchers, R.J. Bienstock, K.B. Tomer. Mass spectrometric characterization of the glycosylation pattern of HIV-gp120 expressed in CHO cells. Biochem., 39:11194-11204, 2000.[Abstract ]
  100. Parker, C.E., K.B. Tomer. Epitope mapping by a combination of epitope excision and MALDI/MS. In: Chapman, J., (ed.): Protein and peptide analysis: advances in the use of mass spectrometry, vol. 146 of Methods in Molecular Biology, Humana, Totowa, NJ, 185-201, 2000.[Abstract ]
  101. Zhou, W., B.A. Merrick, M.G. Khaledi, K.B. Tomer. Detection and sequencing of phosphopeptides affinity bound to immobilized metal ion beads by matrix-assisted laser desorption/ionization mass spectrometry. J. Amer. Soc. Mass Spectrom., 11:273 282, 2000. [Abstract ]
  102. Deterding, L.J., R., Prasad, G.P. Mullen, S.H. Wilson, K.B Tomer. Mapping of the 5'-2-deoxyribose-5-phosphate lyase active site in DNA polymerase by mass spectrometry. J. Biol. Chem., 275(14):10463-10471, 2000. [Abstract ]
  103. Chen, Y.-R., L.J. Deterding, K.B. Tomer, R.P. Mason. The nature of the inhibition of horseradish peroxidase and mitochondrial cytochrome c oxidase by cyanyl radical. Biochem., 39(15): 4415-4422, 2000. [Abstract ]
  104. Hochleitner, E.O., C. Borchers, C. Parker, R.J. Bienstock, K.B. Tomer. Characterization of a discontinuous epitope of the human immunodeficiency virus (HIV) core protein p24 by epitope excision and differential chemical modification followed by mass spectrometric peptide mapping analysis. Protein Sci., 9: 487-496, 2000. [Abstract ]
  105. Borchers, C., J.F. Peter, M.C. Hall, T.A. Kunkel, K.B. Tomer. Identification of In Gel Digested Proteins by Complementary Peptide-Mass Fingerprinting and Tandem Mass Spectrometry Data Obtained on an Electrospray Ionization Quadrupole Time-of Flight Mass Spectrometer. Anal. Chem., 72:1163-1168, 2000.[Abstract ]
  106. Hochleitner, E.O., M.K. Gorny, S. Zolla-Pazner, K.B. Tomer. Mass spectrometric characterization of a discontinuous epitope of the human immunodeficiency virus (HIV) envelope protein HIV-gp120 recognized by the human monoclonal antibody 1331A. J. Immunol., 164(8): 4156-4161, 2000. [Abstract ]

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