Environmental Cardiopulmonary Disease Group
Allergy & Asthma
-
-
Darryl C. Zeldin, M.D.
Scientific Director and Principal Investigator -
Tel (919) 541-1169
Fax (919) 541-4214
zeldin@niehs.nih.gov -
P.O. Box 12233
Mail Drop A2-05
Research Triangle Park, North Carolina 27709
Delivery Instructions
Research Summary
The Environmental Cardiopulmonary Disease Group is active in clinical research on asthma and the environment. The group's research focuses on indoor allergen exposures, and other potential risk factors and modifying factors (e.g. endotoxin), which are associated with the development and exacerbation of allergic respiratory diseases. The group has conducted large national studies which have not only resulted in a better understanding of the characteristics and predictors of indoor allergen and endotoxin exposures in U.S. households, but also have provided information on the importance of different allergens in asthma and other allergic diseases that are of significant public health concerns nationally and globally. The main goal of the group is to provide sound scientific basis for the development and implementation of environmental interventions that will be effective in preventing asthma and other allergic diseases.
Major area of research:
- Asthma: Exposure Assessment and Prevention ("/Rhythmyx/assembler/render?sys_contentid=52986&sys_revision=2&sys_variantid=639&sys_context=0&sys_authtype=0&sys_siteid=&sys_folderid=" sys_dependentvariantid="639" sys_dependentid="52986" inlinetype="rxhyperlink" rxinlineslot="103" sys_dependentid="52986" sys_siteid="" sys_folderid="")
Current projects:
- Determining the prevalence and determinants of indoor allergen and endotoxin exposures and investigating the complex relationships between those exposures, allergic sensitization, and the development and exacerbation of allergic diseases, including asthma
- Developing environmental interventions that lower indoor exposures to allergens and endotoxin
Darryl C. Zeldin, M.D., is Scientific Director and head of the Molecular & Cellular Biology and Environmental Cardiopulmonary Groups in the Laboratory of Respiratory Biology. He earned a B.A. in chemistry from Boston University in 1982 and an M.D. from Indiana University School of Medicine in 1986. He completed a Residency in Internal Medicine at Duke University in 1989 and a Fellowship in Pulmonary/Critical Care Medicine at Vanderbilt University in 1993. Zeldin, a physician-scientist who is internationally recognized for his contributions to the fields of environmental health, respiratory disease and cardiovascular disease, is a member of the American Society for Clinical Investigation (ASCI), a Fellow in the American College of Chest Physicians and a Fellow in the American Heart Association. He has served on NIH and foundation study sections and is a member of the editorial boards of several scientific journals. He has published over 200 peer-reviewed articles in leading biomedical journals, as well as numerous reviews and book chapters. Zeldin is on staff at Duke University Medical Center, where he serves as an attending physician on the pulmonary consult service and the medical intensive care unit. He served as the NIEHS Acting Clinical Director from 2007-2011 and will serve as the NIEHS Scientific Director beginning in October 2011.
