Bauer, B., Hartz, A.M.S., Fricker, G., and Miller, D.S. Pregnane X receptor upregulation of p-glycoprotein expression and transport function at the blood-brain barrier. Mol. Pharmacol., 66:413-419, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15322232)
Hartz, A.M.S., Bauer, B., Fricker, G., and Miller, D.S. Rapid regulation of p-glycoprotein at the blood-brain barrier by endothelin-1. Mol. Pharmacol., 66:387-394, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15322229)
Sykes, D., Sweet, D.H., Lowes, S., Nigam, S.J., Pritchard, J.B., and Miller, D.S. Organic Anion Transport in Choroid Plexus From Wild-Type and Organic Anion Transporter 3 (Slc22a8)-Null Mice. Am. J. Physiol., 286:F972-8, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15075193)
Breen, C.M., Sykes, D.B., Baehr, C., Fricker, G., and Miller, D.S. Fluorescein-Methotrexate Transport in rat choroid plexus analyzed using confocal microscopy. Am. J. Physiol., 287:F562-F569, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15126245)
Miller, D.S. Confocal imaging of xenobiotic transport across the choroid plexus. Adv. Drug Delivery Rev., 56:1811-1824, 2004. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15381335)
Bauer, B., Hartz, A.M.S., Fricker, G., and Miller, D.S. Modulation of p-glycoprotein transport function at the blood-brain barrier. Experimental Biology and Medicine, 230:118-27, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15673560)
Pritchard, J.B., and Miller, D.S. Expression systems for cloned polyspecific xenobiotic transporters. Toxicol. Appl. Pharmacol., 204:256-262, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15845417)
Lowes, S., Sykes, D., Breen, C.R., Ragone, L.J., and Miller, D.S. Multiple components of 2,4-dichlorophenoxyacetic acid uptake by rat choroid plexus. J. Pharmacol. Exp. Therap., 315:136-143, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15958719)
Hartz, A.M.S., Bauer, B., Baehr, C.H., Miller D.S., and Fricker, G. Drug delivery across the blood-brain barrier. Current Nanoscience, 1:203-209, 2005.
Zhang, W., Wang, T., Pei, Z., Miller, D.S., Wu, X., Block, M.L., Wilson, B., Zhang, W., Zhou, Y., Hong, J.-S., and Zhang, J. Aggregated α-Synuclein activates microglia: a process leading to disease progression in Parkinson’s disease. FASEB J., 19:533-42, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15791003)
Wang, T., Pei, Z., Zhang, W., Liu, B., Langenbach, R., Lee, C., Wilson, B., Reece, J.M., Miller, D.S, and Hong, J.S. MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration. FASEB J., 19:1134-6, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15845609)
Hartz, A.M.S., Bauer, B., Fricker, G., and Miller, D.S. Rapid modulation of p-glycoprotein-mediated transport at the blood-brain barrier by TNF-α and LPS. Mol. Pharm., 69:462-470, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16278373)
Dallas, S., Miller, D.S., and Bendayan, R. Multidrug resistance-associated proteins (MRPs): Expression and function in the central nervous system. Pharmacol. Rev., 58:140-161, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16714484)
Wang, T., Zhang, W., Pei, Z., Block, M., Wilson, B., Reece, J.M., Miller, D.S., and Hong, J.S. Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. FASEB J.20:906-15, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16675848)
Bauer, B., Yang, X., Hartz, A.M., Olson, E.R., Zhao, R., Kalvass, J.C., Pollack, G.M., and Miller, D.S. In vivo activation of human PXR tightens the blood-brain barrier to methadone through P-glycoprotein upregulation. Mol Pharm, 70:1212-1219, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16837625)
Hartz, A.M.S., Bauer, B., Fricker, G., and Miller, D.S. Rapid modulation of p-glycoprotein-mediated transport at the blood-brain barrier by TNF-α and LPS. Mol. Pharm., 69:462-470, 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16278373)
Bauer, B., Hartz, A.M.S., and Miller, D.S. TNF-α and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Mol. Pharm., 71:667-75, 2001, 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17132686)
Zhang, W., Dallas, S., Zhang, D., Guo, J-P., Pang, H., Wilson, B., Miller, D.S., Chen, B., Zhang, W., McGeer, P.L., Hong, J-S., and Zhang, J. Microglial PHOX and Mac-1 are essential to the enhanced dopaminergicneurodegeneration elicited by A30P and A53T mutant α-synuclein. Glia, 55:1178-88, 2007. [Abstract](http://www.ncbi.nlm.nih.gov/pubmed/17600340?ordinalpos=16&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Pei, Z., Pang, H., Wang, T., Zhang, W., Wu, X., Dallas, S., Wilson, B., Reece, J., Miller, D.S., Hong, J-S., and Block, M.L. MAC1 mediates LPS-induced superoxide from microglia: the role of phagocytosis receptors in dopaminergic neurotoxicity. Glia, 55:1362-73, 2007. [Abstract](http://www.ncbi.nlm.nih.gov/pubmed/17654704?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Hartz, A.M.S., Bauer, B., Block, M.L., Hong, J.-S., and Miller, D.S. Diesel exhaust particles induce oxidative stress, pro-inflammatory signaling, and P-glycoprotein upregulation at the blood-brain barrier. FASEB J., 22:2723-2733, 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18474546)
Bauer, B., Hartz, A.M., Pekcec, A., Toellner, K., Miller, D.S., and Potschka, H. Seizure-induced upregulation of P-glycoprotein at the blood-brain barrier through glutamate and COX-2 signaling. Mol Pharm, 73:329-41, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18094072?ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Bauer, B., Hartz, A.M., Yang, X., Lucking, J.R., Pollack, G.M., and Miller, D.S. Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTÀ, at the blood-brain barrier. J Cerebral Blood Flow Metab, 28:1222-1234, 2008. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18349876?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Miller, D.S., Bauer, B., and Hartz, A.M.S. Modulation of p-glycoprotein at the blood-brain barrier: opportunities to improve CNS pharmacotherapy. Pharmacol. Rev., 60:196-209, 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18560012 )
|