Miyakawa H, Mason RP, Jiang J-J, Kadiiska MB. Lipid-derived free radical production in superantigen-induced interstitial pneumonia. Free radical biology & medicine 47(3):241-249; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19376221)
Chatterjee, S., Lardinois, O.M., Bonini, M.G., Bhattacharjee, S., Stadler, K., Corbett, J., Deterding, L.G., Tomer, K.B., Kadiiska, M., Mason, R.P. Site-specific CPB1 tyrosine nitration and its patho-physiological implications following coupling with NOS-3 in experimental sepsis. Journal of immunology, Baltimore, Md. 183(6):4055-4066; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19717511)
Lardinois, O.M., Maltby, D.A., Medzihradszky, K.F., Ortiz de Montellano, P.R., Tomer, K.B., Mason, R.P., Deterding, L.J. Spin Scavenging Analysis of Myoglobin Protein-Centered Radicals Using Stable Nitroxide Radicals: Characterization of Oxoammonium Cation-Induced Modifications. Chemical Research in Toxicology 22(6):1034-1049; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19449826)
Chatterjee, S., Ehrenshaft, M., Bhattacharjee, S., Deterding, L.J., Bonini, M.G., Corbett, J., Kadiiska, M., Tomer, K.B., Mason, R.P. Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. Free radical biology & medicine 46(4):454-461; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19049863)
Ehrenshaft, M., de Oliveira Silva, S., Perdivara, I., Bilski, P., Sik, R.H., Chignell, C.F., Tomer, K.B., Mason, R.P. Immunological detection of N-formylkynurenine in oxidized proteins. Free radical biology & medicine 46(9):1260-1266; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19353782)
Brimfield, A.A., Mancebo, A.M., Mason, R.P., Jiang, J., Sirak, A.G., Novak, M.J. Free radical production from the interaction of 2-chloroethyl vesicants (mustard gas) with pyridine nucleotide-driven flavoprotein electron transport systems. Toxicology and applied pharmacology 234(1):128-134; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18977373)
Ramirez, D.C., Gomez-Mejiba, S.E., Corbett, J.T., Deterding, L.J., Tomer, K.B., Mason, R.P. Cu,Zn-superoxide dismutase-driven free radical modifications: copper- and carbonate radical anion-initiated protein radical chemistry. Biochem J. 417(1):341-53; 2009. [Abstract](http://www.ncbi.nlm.nih.gov/pubmed/18764780?ordinalpos=19&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Liu, J., Qian, S.Y., Guo, Q., Jiang, J., Waalkes, M.P., Mason, R.P., Kadiiska, M.B. Cadmium generates reactive oxygen-and carbon-centered radical species in rats: insights from in vivo spin-trapping studies. Free radical biology & medicine 45(4):475-481; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18501199)
Bonini, M.G., Stadler, K., Silva, S.O., Corbett, J., Dore, M., Petranka, J., Fernandes, D.C., Tanaka, L.Y., Duma, D., Laurindo, F.R.M, Mason, R.P. Constitutive nitric oxide synthase activation is a significant route for nitroglycerin-mediated vasodilation. Proceedings of the National Academy of Sciences of the United States of America 105(25):8569-8574; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18562300)
Cassina, P., Cassina, A., Pehar, M., Castellanos, R., Gandelman, M., de León, A., Robinson, K.M., Mason, R.P., Beckman, J.S., Barbeito, L., Radi, R. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants. J Neurosci. 28(16):4115-22; 2008. [Abstract]http://www.ncbi.nlm.nih.gov/pubmed/18417691?ordinalpos=63&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Connor, H.D., Sturgeon, B.E., Mottley, C., Sipe, H.J., Mason, R.P. L-tryptophan radical cation electron spin resonance studies: connecting solution-derived hyperfine coupling constants with protein spectral interpretations. J Am Chem Soc. 130: 6381-6387; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18433127)
Chatterjee, S., Ehrenshaft, M., Bhattacharjee, S., Deterding, L.J., Bonini, M.G., Corbett, J., Kadiiska, M., Tomer, K.B., Mason, R.P. Immunospin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. Free Radic Biol Med. 2008. [Abstract]http://www.ncbi.nlm.nih.gov/pubmed/19049863?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Lardinois, O.M., Detweiler, C.D., Tomer, K.B., Mason, R.P., Deterding, L.J. Identifying the site of spin trapping in proteins by a combination of liquid chromatography, ELISA and off-line tandem mass spectrometry. Free Radical Biology & Medicine 44(5):893-906; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18160050)
Lardinois, O.M., Tomer, K.B., Mason, R.P., Deterding, L.J. Identification of protein radicals formed in the human neuroglobin-H2O2 reaction using immuno-spin trapping and mass spectrometry. Biochemistry 47(39):10440-10448; 2008. [Abstract]http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18767815
Liu, J., Qian, S.Y., Guo, Q., Jiang, J., Waalkes, M.P., Mason, R.P., Kadiiska, M.B. Cadmium generates reactive oxygen- and carbon-centered radical species in rats: insights from in vivo spin-trapping studies. Free Radic Biol Med. 45(4):475-81; 2008. [Abstract]http://www.ncbi.nlm.nih.gov/pubmed/18501199?ordinalpos=45&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Ranguelova, K., Suarez, J., Magliozzo, R.S., Mason, R.P. Immuno-spin investigation of peroxide- and isoniazid-induced radicals in mycobacterium tuberculosis catalase-peroxidase. Biochemistry 47(43):11377-11385; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18831539)
Rehman, H., Connor, H.D., Ramshesh, V.K., Theruvath, T.P., Mason, R.P. Wright, G.L., Lemasters, J.J., Zhong, Z. Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts. Transplantation 85(9):1322-1331; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18475191)
Siraki, A.G., Deterding, L., Bonini, M.G., Jiang, J.J., Ehrenshaft, M., Mason, R.P. Procainamide but not N-acetylprocainamide induces protein free radical formation on myeloperoxidase: A potential mechanism of agranulocytosis. Chemical Research in Toxicology 21(5):1143-1153; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18489081)
Stadler, K., Bonini, M.G., Dallas, S., Jiang, J.J., Radi, R., Mason, R.P., Kadiiska, M. Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes. Free radical biology & medicine 45(6):866-874; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18620046)
Stadler, K., Bonini, M.G., Dallas, S., Duma, D., Mason, R.P., Kadiiska, M.B. Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis. American journal of physiology. Endocrinology and metabolism 295(2):E456-E462; 2008. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18559982)
Bhattacharjee, S., Deterding, L.J., Jiang, J.J., Bonini, M.G., Tomer, K.B., Ramirez, D.C., Mason, R.P. Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. Journal of the American Chemical Society 129(44):13493-13501; 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17939657)
Bonini, M.G., Siraki, A.G., Bhattacharjee, S., Mason, R.P. Glutathione-induced radical formation on lactoperoxidase does not corelate with the enzyme’s peroxidase activity. Free Radical Biol. Med. 42:985-992; 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17349926&query_hl=10&itool=pubmed_docsum)
Deterding, L.J., Bhattacharjee, S., Ramirez, D.C., Mason, R.P., Tomer, K.B. Top-down and bottom-up mass spectrometric characterization of human myoglobin-centered free radicals induced by oxidative damage. Anal Chem. 79(16):6236-48; 2007. (Abstract) [Abstract]http://www.ncbi.nlm.nih.gov/pubmed/17637042?ordinalpos=120&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Jiang, J.J., Corbett, B.J., Hogg, N., Mason, R.P. An electron paramagnetic resonance investigation of the oxygen dependence of the arterial-venous gradient of nitrosyl hemoglobin (HbNO) in blood circulation. Free Radical Biology & Medicine 8:1208-1215; 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17854716)
Ramirez, D.C., Gomez-Mejiba, S.E., Mason, R.P. Immuno-spin trapping analyses of DNA radicals. Nature Protocols 2:512-522; 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17406615&query_hl=16&itool=pubmed_docsum)
Siraki, A.G., Bonini, M.G., Jiang, J., Ehrenshaft, M., Mason, R.P. Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. Chem Res Toxicol. 20(7):1038-45; 2007. [Abstract]http://www.ncbi.nlm.nih.gov/pubmed/17602675?ordinalpos=124&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum
Woods, C.G., Burns, A.M., Maki, A., Bradford, B.U., Cunningham, M.L., Connor, H.D., Kadiiska, M.B., Mason, R.P., Peters, J.M., Rusyn, I. Sustained formation of ?-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-?, but not NADPH oxidase. Free Radical Biol. Med. 42:335-342; 2007. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17210446&query_hl=7&itool=pubmed_docsum)
Bonini, M.G., Rota, C., Tomasi, A., Mason, R.P. The oxidation of 2’,7’-dichlorofluorescin to reactive oxygen species: A self-fulfilling prophesy? Free Radical Biol. Med. 40: 968- 975; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16540392)
Ehrenshaft, M., Mason, R.P. Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping. Free Radical Biol. Med. 41:422-430; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16843823)
Keszler, A., Mason, R.P., Hogg, N. Immuno-spin trapping of hemoglobin and myoglobin radicals from nitrite-mediated oxidation. Free Radical Biol. Med. 40:507-515; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16443166)
Kono, H., Woods, C.G., Maki, A., Connor, H.D., Mason, R.P., Rusyn, I., Fujii, H. Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage. Free Rad. Res. 40:579-588; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16753835)
Nakai, K., Kadiiska, M.B., Jiang, J.J., Stadler, K., Mason, R.P. Free Radical production requires both inducible nitric oxide synthase and xanthine oxidase in LPS-treated skin. Natl. Acad. Sci. USA.103:4616-4621; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16537416)
Ramirez, D.C., Gomez Mejiba, S.E., Mason, R.P. Immuno-spin trapping of DNA radicals. Nature Methods 3 (2): 123-127; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16432522)
Zhong, Z., Connor, H.D., Li, X., Mason, R.P., Forman, D.T., Lemasters, J.J., Thurman, R.G. Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols. J. Pharm. Pharmacol. 58:1533-1543; 2006. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17132217&query_hl=2&itool=pubmed_docsum)
Arimoto T., Kadiiska M.B., Sato K., Corbett J., Mason R.P. Synergistic production of lung free radicals by diesel exhaust particles and endotoxin. Am. J. Respir. Crit. Care Med. 171:379-387, 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15477498)
Detweiler, C.D., Lardinois, O.M., Deterding, L.J., Ortiz de Montellano, P.R., Tomer, K.B., Mason, R.P. Identification of the myoglobin tyrosyl radical by immuno-spin trapping and its dimerization. Free Radic. Biol. Med. 38:969-976; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15749393)
Dikalov, S., Jiang, J., Mason R.P. Characterization of the high-resolution ESR spectra of superoxide radical adducts of 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide (DEPMPO) and 5,5-dimethyl-1-pyrroline N-oxide (DMPO). Analysis of conformation exchange. Free Radic. Res. 39(8):825-836; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16036362)
Kadiiska, M.B., Gladen, B.C., Baird, D.D., Germolec, D., Graham, L.B., Parker, C.E., Nyska, A., Wachsman, J.T., Ames, B.N., Basu, S., Brot, N., FitzGerald, G.A., Floyd, R.A., George, M., Heinecke, J.W., Hatch, G.E., Hensley, K., Lawson, J.A., Marnett, L.J., Morrow, J.D., Murray, D.M., Plastaras, J., Roberts, L.J., Rokach, J., Shigenaga, M.K., Sohal, R.S., Sun, J., Tice, R.R., Van Thiel, D.H., Wellner, D., Walter, P.B., Tomer, K.B., Mason, R.P., Barrett, J.C. Biomarkers of Oxidative Stress Study II. Are Oxidation Products of Lipids, Proteins and DNA Markers in CCl4 Poisoning? Free Radical Biol. Med. 38:698-710; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15721980)
Kadiiska, M.B., Gladen, B.C., Baird, D.D., Graham, L.B., Parker, C.E., Ames, B.N., Basu, S., FitzGerald, G.A., Lawson, J.A., Marnett, L.J., Morrow, J.D., Murray, D.M., Plastaras, J., Roberts, L.J., Rokach, J., Shigenaga, M.K., Sun, J., Walter, P.B., Tomer, K.B., Barrett, J.C., Mason, R.P. Biomarkers of Oxidative Stress Study III. Effects of the Non-Steroidal Anti-Inflammatory Agents Indomethacin and Meclofenamic acid on Measurements of Oxidative Products of Lipids in CCl4 Poisoning. Free Radical Biol. Med. 38:711-718; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15721981)
Nakai, K., Mason, R.P. Immunochemical detection of nitric oxide and nitrogen dioxide trapping of the tyrosyl radical and the resulting nitrotyrosine in sperm whale myoglobin. Free Radical Biol. Med. 39:1050-1058; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16198232)
Qian, S.Y., Kadiiska, M.B., Guo, Q., Mason, R.P. A novel protocol to identify and quantify all spin trapped free radicals from in vitro/in vivo interaction of HO• and DMSO: LC/ESR, LC/MS, and dual spin trapping combinations. Free Radic. Biol. Med. 38:125-135; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15589381)
Ramirez, D.C., Gomez Mejiba, S.E., Mason, R.P. Copper-catalyzed protein oxidation and its modulation by carbon dioxide: enhancement of protein radicals in cells. J. Biol. Chem. 280:27402-27411; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15905164)
Ramirez, D.C., Gomez Mejiba, S.E., Mason, R.P. Mechanism of hydrogen peroxide-induced Cu, Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping. Free Radical Biol. Med. 38:201-214; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15607903)
Zhong, Z., Conner, H.D., Frosh, M., Bunzedahl, H., Lind, H., Lehnert, M., Mason, R.P., Thurman, R.G., Lemasters, J.J. Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology 129:652-664; 2005. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16083719)
|