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Selected Publications

Free Radical Metabolism Group

  1. Rehman H, Connor HD, Ramshesh VK, Theruvath TP, Mason RP , Wright GL, Lemasters JJ, Zhong Z. Ischemic preconditioning prevents free radical production and mitochondrial depolarization in small-for-size rat liver grafts. Transplantation 2008 85(9):1322-1331. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18475191) Exit NIEHS
  2. Lardinois OM, Detweiler CD , Tomer KB, Mason RP , Deterding LJ. Identifying the site of spin trapping in proteins by a combination of liquid chromatography, ELISA and off-line tandem mass spectrometry. Free radical biology & medicine 2008 44(5):893-906. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=18160050) Exit NIEHS
  3. Bhattacharjee S, Deterding LJ, Jiang JJ, Bonini MG, Tomer KB, Ramirez DC, Mason RP. Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. Journal of the American Chemical Society 2007 129(44):13493-13501. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17939657) Exit NIEHS
  4. Jiang JJ, Corbett BJ, Hogg N, Mason RP. An electron paramagnetic resonance investigation of the oxygen dependence of the arterial-venous gradient of nitrosyl hemoglobin (HbNO) in blood circulation. Free radical biology & medicine 8:1208-1215, 2007. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17854716) Exit NIEHS
  5. Bhattacharjee S, Deterding LJ, Jiang JJ, Bonini MG, Tomer KB, Ramirez DC, Mason RP. Electron transfer between a tyrosyl radical and a cysteine residue in hemoproteins: spin trapping analysis. Journal of the American Chemical Society 44:13493-13501, 2007. [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=17939657) Exit NIEHS
  6. Ramirez, D.C., Gomez-Mejiba, S.E., Mason, R.P. : Immuno-spin trapping analyses of DNA radicals. Nature Protocols 2:512-522, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17406615&query_hl=16&itool=pubmed_docsum) Exit NIEHS
  7. Bonini, M.G., Siraki, A.G., Bhattacharjee, S., Mason, R.P. : Glutathione-induced radical formation on lactoperoxidase does not corelate with the enzyme’s peroxidase activity. Free Radical Biol. Med. 42:985-992, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17349926&query_hl=10&itool=pubmed_docsum) Exit NIEHS
  8. Bonini, M.G., Siraki, A.G., Atanassov, B.S., Mason, R.P. : Immunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytes. Free Radical Biol. Med. 42:530-540, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17275685&query_hl=10&itool=pubmed_docsum) Exit NIEHS
  9. Woods, C.G., Burns, A.M., Maki, A., Bradford, B.U., Cunningham, M.L., Connor, H.D., Kadiiska, M.B., Mason, R.P., Peters, J.M., Rusyn, I.: Sustained formation of α-(4-pyridyl-1-oxide)-N-tert-butylnitrone radical adducts in mouse liver by peroxisome proliferators is dependent upon peroxisome proliferator-activated receptor-α, but not NADPH oxidase. Free Radical Biol. Med. 42:335-342, 2007.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17210446&query_hl=7&itool=pubmed_docsum) Exit NIEHS
  10. Zhong, Z., Connor, H.D., Li, X., Mason, R.P., Forman, D.T., Lemasters, J.J., Thurman, R.G. Reduction of ciclosporin and tacrolimus nephrotoxicity by plant polyphenols. J. Pharm. Pharmacol. 58:1533-1543; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17132217&query_hl=2&itool=pubmed_docsum) Exit NIEHS
  11. Kono, H., Woods, C.G., Maki, A., Connor, H.D., Mason, R.P., Rusyn, I., Fujii, H. Electron spin resonance and spin trapping technique provide direct evidence that edaravone prevents acute ischemia-reperfusion injury of the liver by limiting free radical-mediated tissue damage. Free Rad. Res. 40:579-588; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16753835) Exit NIEHS
  12. Ehrenshaft, M., Mason, R.P. Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping. Free Radical Biol. Med. 41: 422-430; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16843823) Exit NIEHS
  13. Nakai, K., Kadiiska, M.B., Jiang, J.-J., Stadler, K., Mason, R.P. Free Radical production requires both inducible nitric oxide synthase and xanthine oxidase in LPS-treated skin. Natl. Acad. Sci. USA.103: 4616-4621; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16537416) Exit NIEHS
  14. Bonini, M.G., Rota, C., Tomasi, A., Mason, R.P. The oxidation of 2’,7’-dichlorofluorescin to reactive oxygen species: A self-fulfilling prophesy? Free Radical Biol. Med. 40: 968- 975; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16540392) Exit NIEHS
  15. Keszler, A., Mason, R.P., Hogg, N. Immuno-spin trapping of hemoglobin and myoglobin radicals from nitrite-mediated oxidation. Free Radical Biol. Med. 40: 507-515; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16443166) Exit NIEHS
  16. Ramirez, D.C., Gomez Mejiba, S.E. & Mason, R.P. Immuno-spin trapping of DNA radicals. Nature Methods 3 (2): 123-127; 2006.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16432522) Exit NIEHS
  17. Nakai, Kozo and Mason, R.P. Immunochemical detection of nitric oxide and nitrogen dioxide trapping of the tyrosyl radical and the resulting nitrotyrosine in sperm whale myoglobin. Free Radical Biol. Med. 39:1050-1058; 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16198232) Exit NIEHS
  18. Ramirez D.C., Gomez Mejiba S.E., Mason R.P. Copper-catalyzed protein oxidation and its modulation by carbon dioxide: enhancement of protein radicals in cells. J. Biol. Chem. 280: 27402-27411; 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15905164) Exit NIEHS
  19. Zhong Z., Conner H.D., Frosh M., Bunzedahl H., Lind H., Lehnert M., Mason R.P., Thurman R.G., Lemasters J.J. Free radical-dependent dysfunction of small-for-size rat liver grafts: prevention by plant polyphenols. Gastroenterology 129: 652-664; 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16083719) Exit NIEHS
  20. Dikalov S., Jiang J., Mason R.P. Characterization of the high-resolution ESR spectra of superoxide radical adducts of 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide (DEPMPO) and 5,5-dimethyl-1-pyrroline N-oxide (DMPO). Analysis of conformation exchange. Free Radic. Res. 39(8): 825-836; 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16036362) Exit NIEHS
  21. Detweiler C.D., Lardinois O.M., Deterding L.J., Ortiz de Montellano P.R., Tomer K.B., Mason R.P. Identification of the myoglobin tyrosyl radical by immuno-spin trapping and its dimerization. Free Radic. Biol. Med. 38: 969-976; 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15749393) Exit NIEHS
  22. Arimoto T., Kadiiska M.B., Sato K., Corbett J., Mason R.P. Synergistic production of lung free radicals by diesel exhaust particles and endotoxin. Am. J. Respir. Crit. Care Med. 171: 379-387, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15477498) Exit NIEHS
  23. Kadiiska, M.B., Gladen, B.C., Baird, D.D., Graham, L.B., Parker, C.E., Ames, B.N., Basu, S., FitzGerald, G.A., Lawson, J.A., Marnett, L.J., Morrow, J.D., Murray, D.M., Plastaras, J., Roberts, L.J., Rokach, J., Shigenaga, M.K., Sun, J., Walter, P.B., Tomer, K.B., Barrett, J.C., Mason, R.P. Biomarkers of Oxidative Stress Study III. Effects of the Non-Steroidal Anti-Inflammatory Agents Indomethacin and Meclofenamic acid on Measurements of Oxidative Products of Lipids in CCl4 Poisoning. Free Radical Biol. Med. 38: 711-718, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15721981) Exit NIEHS
  24. Kadiiska, M.B., Gladen, B.C., Baird, D.D., Germolec, D., Graham, L.B., Parker, C.E., Nyska, A., Wachsman, J.T., Ames, B.N., Basu, S., Brot, N., FitzGerald, G.A., Floyd, R.A., George, M., Heinecke, J.W., Hatch, G.E., Hensley, K., Lawson, J.A., Marnett, L.J., Morrow, J.D., Murray, D.M., Plastaras, J., Roberts, L.J., Rokach, J., Shigenaga, M.K., Sohal, R.S., Sun, J., Tice, R.R., Van Thiel, D.H., Wellner, D., Walter, P.B., Tomer, K.B., Mason, R.P., Barrett, J.C. Biomarkers of Oxidative Stress Study II. Are Oxidation Products of Lipids, Proteins and DNA Markers in CCl4 Poisoning? Free Radical Biol. Med. 38: 698-710, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15721980) Exit NIEHS
  25. Ramirez, D.C., Gomez Mejiba, S.E., Mason, R.P. Mechanism of hydrogen peroxide-induced Cu, Zn-superoxide dismutase-centered radical formation as explored by immuno-spin trapping. Free Radical Biol. Med. 38: 201-214, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15607903) Exit NIEHS
  26. Qian, S.Y., Kadiiska M.B., Guo, Q., Mason R.P. A novel protocol to identify and quantify all spin trapped free radicals from in vitro/in vivo interaction of HO• and DMSO: LC/ESR, LC/MS, and dual spin trapping combinations. Free Radic. Biol. Med. 38: 125-135, 2005.  [Abstract] (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15589381) Exit NIEHS

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Last Reviewed: June 30, 2008