Selected Publications

Environmental Genomics Group

1. Noureddine, M. A., Menendez, D., Campbell, M. R., Bandele, O. J., Horvath, M. M., Wang, X., Pittman, G. S., Chorley, B. N., Resnick, M. A., and Bell, D. A. (2009) Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts. PLoS Genet 5:e1000462. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/19424414?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
2. Jordan, J. J., Menendez, D., Inga, A., Nourredine, M., Bell, D., and Resnick, M. A. (2008) Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. PLoS Genet 4:e1000104. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18714371?ordinalpos=9&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
3. Chorley, B. N., Wang, X., Campbell, M. R., Pittman, G. S., Noureddine, M. A., and Bell, D. A. (2008) Discovery and verification of functional single nucleotide polymorphisms in regulatory genomic regions: current and developing technologies. Mutat Res 659:147-157. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18565787?ordinalpos=10&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
4. Horvath, M. M., Wang, X, Resnick, M.A., Bell, D.A. (2007) Divergent evolution of human p53 binding sites: cell cycle vs apoptosis. PloS Genet 3:e127. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17677004?ordinalpos=14&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
5. Wang, X., Tomso, D. J., Chorley, B. N., Cho, H. Y., Cheung, V. G., Kleeberger, S. R., and Bell, D. A. (2007) Identification of polymorphic antioxidant response elements in the human genome. Hum Mol Genet 16:1188-1200. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17409198?ordinalpos=18&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
6. Perera, F.P., Tang, D., Brandt-Rauf, P., Santella, R.M., Mooney, L.V., Tu, Y.H., Bendkowska, I. and Bell, D.A. (2006) Lack of associations among cancer and albumin adducts, ras p21 oncoprotein levels, and CYP1A1, CYP2D6, NAT1, and NAT2 in a nested case-control study of lung cancer within the physicians' health study. Cancer Epidemiol Biomarkers Prev 15, 1417-1419.
7. Novak J.P., Miller, M.C. III, Bell, D.A. (2006) Variation in fiberoptic bead-based oligonucleotide microarrays: dispersion characteristics among hybridization and biological replicate samples. Biol Direct 1, 18. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/16787528?ordinalpos=26&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
8. Tomso, D. J., Inga, A., Menendez, D., Pittman, G. S., Campbell, M. R., Storici, R., Bell, D. A.,  Resnick, M. A. (2005) Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation. Proc Natl Acad Sci USA 102:6431-6436. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/15843459?ordinalpos=36&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
9. Liu, X., Campbell, M. R., Pittman, G. S., Faulkner, E. C., Watson, M. A., Bell, D. A. (2005) Expression-based discovery of variation in the human glutathione S-transferase M3 promoter and functional analysis in a glioma cell line using allele-specific chromatin immunoprecipitation. Cancer Res 65, 99-104. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/15665284?ordinalpos=38&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
10. Tomso, D. J. and Bell, D. A. (2003) Sequence context at human single nucleotide polymorphisms: overrepresentation of CpG dinucleotide at polymorphic sites and suppression of variation in CpG islands. J Mol Biol 327, 303-308. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/12628237?ordinalpos=64&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
11. Perera, F. P., Mooney, L. A., Stampfer, M., Phillips, D. H., Bell, D. A. (2002) Associations between carcinogen-DNA damage, glutathione S-transferase genotypes, and risk of lung cancer in the prospective Physicians' Health Cohort Study. Carcinogenesis 23, 1641-1646. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/12376472?ordinalpos=68&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
12. Fritsche, E., Baek, S. J., King, L. M., Zeldin, D. C., Eling, T. E., Bell, D. A. (2001) Functional characterization of cyclooxygenase-2 polymorphisms. J Pharmacol Exp Ther 299, 468-476. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/11602656?ordinalpos=77&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
13. Whyatt, R. M., Perera, F. P., Jedrychowski, W., Santella, R. M., Garte, S., Bell, D. A. (2000) Association between polycyclic aromatic hydrocarbon-DNA adduct levels in maternal and newborn white blood cells and glutathione S-transferase P1 and CYP1A1 polymorphisms. Cancer Epidemiol Biomarkers Prev 9, 207-212. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/10698483?ordinalpos=99&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
14. Fennell, T. R., MacNeela, J. P., Morris, R. W., Watson, M., Thompson, C. L., Bell, D. A. (2000) Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione S-transferase T1-null and M1-null genotypes. Cancer Epidemiol Biomarkers Prev 9, 705-712. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/10919741?ordinalpos=86&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
15. Lunn, R. M., Langlois, R. G., Hsieh, L. L., Thompson, C. L., Bell, D. A. (1999) XRCC1 polymorphisms: effects on aflatoxin B1-DNA adducts and glycophorin A variant frequency. Cancer Res 59, 2557-2561. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/10363972?ordinalpos=111&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
16. Taylor, J. A., Umbach, D. M., Stephens, E., Castranio, T., Paulson, D., Bell, D. A. (1998) The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction. Cancer Res 58, 3603-3610. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/9721868?ordinalpos=124&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
17. Bell, D.A., Taylor, J.A., Paulson, D.F., Robertson, C.N., Mohler, J.L. and Lucier, G.W. (1993) Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-transferase M1 (GSTM1) that increases susceptibility to bladder cancer. J Natl Cancer Inst, 85, 1159-1164. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/8320745?ordinalpos=198&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)

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