Necropsy Support

Pathology Support Group

Necropsy Support is a fully equipped necropsy facility maintained as an adjunct to Histology for use by Institute staff and investigators. The necropsy suite consists of four necropsy work stations and is suited for necropsies of a small number of animals. Investigators are able to perform necropsies themselves or may request any level of support from the Histology staff who are cross-trained in necropsy procedures including tissue collection and fixation. All instruments, solutions and supplies needed to perform necropsies are provided.

Sampling, Trimming and Embedding Guides

The interactive guides and images were created by David Savio and Beth Mahler. Three guides from RITA and NACAD are for organ sampling and trimming in rats and mice. These guides were originally published in Experimental Toxic Pathology, in 2003, Vol. 55, publisher: URBAN & FISCHER

• Revised guides for organ sampling and trimming in rats and mice - Part 1
  • Integumentary system
    • Mammary gland and Skin - CMPB Mammary Gland and Skin trimming examples
    • Zymbal's gland - CMPB Zymbal's examples
    • Clitoral/Preputial gland
  • Digestive system
    • Tongue - CMPB Tongue trimming examples
    • Salivary glands - CMPB Salivary glands examples
    • Pharynx and Larynx (oral study)
    • Esophagus and Trachea (oral study) - CMPB Trachea trimming examples
    • Stomach - CMPB Stomach trimming examples
    • Intestine - CMPB Intestine examples
    • GI Tract - GI Tract sections
    • Liver and Gall bladder (mouse only) - CMPB Liver (mouse and rat) trimming examples
    • Pancreas
• Revised guides for organ sampling and trimming in rats and mice - Part 2
  • Respiratory system
    • Nasal cavity, Nasopharynx and Paranasal sinus - CMPB Nasal Turbinates trimming examples
    • Nasal cavity sections - Palate Palate After Fix Palate sections
    • Nasal cavity sections - Infusion Nasal Cavity Sections
    • Nasal cavity sections - L1 Anterior Section L1 Posteror Section
    • Nasal cavity sections - L2 Anterior Section L2 Posterior Section
    • Nasal cavity sections - L3 Anterior Section L3 Posteror Sections
    • Larynx
    • Trachea (inhalation study) - CMPB Trachea trimming examples
    • Lung - CMPB Thoratic Pluck and Lungs trimming examples
    • Lung - Pre inflation InflateInflated
  • Male genital system - CMPB Male Reproductive system trimming examples
    • Testis and Rete testis - Rat Testies sectioning
    • Epididymis
    • Prostate
  • Female genital system - CMPB Femail Reproductive system trimming examplesFemale uterus bladder trimming examples
    • Ovary and Oviduct
    • Uterus and Vagina
  • Endocrine system
    • Pituitary gland - CMPB Pituitary trimming examples
    • Thyroid gland, Parathyroid gland, Trachea (oral study) and Esophagus - CMPB Thyroid Trachea trimming examples
    • Adrenal gland - CMPB Adrenal examples
• Revised guides for organ sampling and trimming in rats and mice - Part 3
  • Urinary system
    • Kidney and Ureter - CMPB Kidney trimming examples
    • Urinary bladder - CMPB Urinary bladder trimming examples Female Urinary bladder trimming examples
  • Nervous system
    • Brain - CMPB Brain trimming examples
    • Spinal Cord and Spinal nerve root - CMPB Spine trimming examples
    • Eye, Optic nerve and Harderian gland - CMPB Eye trimming examples
  • Musculoskeletal system - CMPB Musculoskeletal trimming examples
    • Skeletal muscle and peripheral nerve
    • Bone, Cartilage, Femur and Joint
  • Cardiovascular system
    • Heart - CMPB Heart trimming examples
    • Aorta
  • Lymphoreticular system
    • Thymus - CMPB Thymus examples
    • Spleen - CMPB Spleen trimming examples
    • Bone marrow (Sternum) - CMPB Sternum trimming examples
    • Bone marrow smear
    • Lymph nodes
• CMPB/NTP Mouse Embedding Suggestions
  • Liver, Gallbladder, Lung, Prostrate, Mesenteric Lymph Nodes, Seminal Vesicle, Urinary Bladder, Testis and Epididymis, Thryoid, Trachea, Esophagus, Parathroid, Kidneys, Adrenals (intact) & Pituitary, Salivary Gland, Heart, Spleen, Aorta, Thymus, & Tounge, Muscle & Sciatic nerve, Skin with Mammary Gland, Intestines & Pancreas, Stomach, Brain & Spinal Cord
• CMPB/NTP Rat Embedding Suggestions
  • Liver, Lung, Prostrate, Mesenteric Lymph Nodes, Seminal Vesicle, Urinary Bladder, Testis and Epididymis, Thryoid, Trachea, Esophagus, Parathroid, Kidneys, Adrenals & Pituitary, Salivary Gland, Heart, Spleen, Aorta, Thymus, & Tounge, Muscle & Sciatic nerve, Skin with Mammary Gland, Intestines & Pancreas, Stomach, Brain & Spinal Cord
• CMPB/NTP Rat Embedding Suggestions
  • Spinal Cord, Nasal Turbinates, Eyes, Harderian glands, Zymbals Gland, Lacrimal Gland, Sternum, Uterine Horns, Mesenteric Lymph Node, Urinary Bladder, Cervix & Vagina, Ovaries with Oviducts, Femur, Clitoral Glands Preputial Glands