Susan Elmore, M.S., D.V.M, D.A.C.V.P., is a staff scientist and board certified pathologist working with David Malarkey, Ph.D., in the NTP Pathology Group Group. She is also Project Officer for the NTP Pathology Support Contract and is primary P.O. for the PAI contract and alternative P.O. for the ILS contract. Other projects include pathology oversight and preparation of the technical reports for the NTP studies of Styrene-Acrylonitrile Trimer, Beta Picoline, Androstenedione, Pulegone, All-Trans-Retinyl Palmitate, Chitosan, Tetrabromobisphenol A and O-Chloropyridine. Elmore also provides pathology oversight for the NTP Immunotox studies Dibenzanthracene, Gum Guggul Extract, Lovastatin, Nelfinavir Mesylate, Resveratrol and 2,3-Butanedione.
Her current focus is on the preparation of a mouse embryo histology atlas. Each organ system will be published separately in the Toxicologic Pathology Journal and when all organ systems are completed, a special issue will be published containing all organ systems. The heart atlas is nearing completion and the atlas of the hepatobiliary system is currently in preparation. Other areas of expertise include immunopathology and renal pathology.
Boards and Committees
STP Historical Control Data Best Practices Working Group (8/06-present)
STP/ACVP Coalition Board of Governors (1/08-present)
STP Symposium Committee (4/08-present)
Editorial Board member of Toxicologic Pathology (1/07-present)
Biography:
Elmore received her B.S. degree in genetics with a minor in biotechnology from NCSU in 1987. She worked as a Research Associate in the lab of Clyde Hutchison, Ph.D. in the UNC Microbiology/Immunology Department from 1987-1997. After graduating from veterinary school at NCSU in 2001, Elmore began her residency in veterinary anatomic pathology, also at NCSU College of Veterinary Medicine. In 2003 she completed her residency and accepted a position as an IRTA fellow at NIEHS in the CMPB/NTP Toxicologic Pathology Training Program. She received her board certification from the American College of Veterinary Pathologists in 2004. Elmore began working as a toxicologic pathologist at Integrated Laboratory Systems, Inc. in 2004 where she served as a contractor for one year, conducting Pathology Working Groups for the NTP and providing pathology services for NIEHS-sponsored research projects. In January of 2006, She joined the Cellular and Molecular Pathology Branch’s staff, accepting a position as an NIEHS staff scientist/NTP pathologist.
Recent Publications
Mac Law and Susan Elmore (2008) Mechanisms of Cell Death. Edited by Robert C. Smart and Ernest Hodgson in : Molecular and Biochemical Toxicology, 4th Edition. John Wiley & Sons, Inc. Hoboken, New Jersey. Chapter 16, pages 287-317.
Alexandra E. Petiet, Matthew H. Kaufman, Matthew M. Goddeeris, Jeffrey Brandenburg, Susan A. Elmore, and G. Allan Johnson (2008). High-resolution magnetic resonance histology of the embryonic and neonatal mouse: A 4D atlas and morphologic database. PNAS 105, 12331-12336. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/18713865?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Elmore, S. A. and Travlos, G. S. (2008; submitted). Chemically Induced Histopathological Changes of the Bone Marrow. Toxicology of the blood and bone marrow – 2nd edition Edited by Jacques Descotes in: Target Organ Toxicology Series (Series Editors John A Thomas, A Wallace Hayes and Donald E Gardner, CRC Press/Taylor and Francis.
Elmore, S. A., Nyska, A. and Tischler, A. S. (2008). The Adrenal Medulla as a Target Organ in Toxicologic Studies of Rats and Mice. Edited by Philip Harvey, David Everett and Christopher Springall in: Target Organ Toxicology Series Vol 26 (Series Editors A Wallace Hayes, John A Thomas and Donald E Gardner, Informa Healthcare.
Tischler, A. S., Nyska, A. and Elmore, S. A. (2008, submitted). Toxic Responses of the Adrenal Medulla in: Volume 11 of Comprehensive Toxicology, 2nd Edition Edited by I. Glenn Sipes, Charlene A. McQueen and A. Jay Gandolfi. Elsevier, New York, NY.
Elmore, S. A. (2007). Apoptosis: a review of programmed cell death (invited review). Toxicol Pathol35 (1-22).
Ramot, Y., Lewis, D. A., Ortel, T. L., Streicker, M., Moser, G., Elmore, S., Ward, S. M., Peddada, S., and Nyska, A. (2007). Age and dose sensitivities in the 2-butoxyethanol F344 rat model of hemolytic anemia and disseminated thrombosis. Exp Toxicol Pathol58 (311-22). [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17261363?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum)
Elmore, S. A. (2006). Enhanced histopathology of mucosa-associated lymphoid tissue. Toxicol Pathol34, 687-96. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17067953?dopt=Abstract)
Elmore, S. A. (2006). Enhanced histopathology of the bone marrow. Toxicol Pathol34, 666-86. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17067952?dopt=Abstract)
Elmore, S. A. (2006). Enhanced histopathology of the thymus. Toxicol Pathol34, 656-65. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17067951?dopt=Abstract)
Elmore, S. A. (2006). Enhanced histopathology of the spleen. Toxicol Pathol34, 648-55. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17067950?dopt=Abstract)
Elmore, S. A. (2006). Enhanced histopathology of the lymph nodes. Toxicol Pathol34, 634-47. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17067949?dopt=Abstract)
Elmore, S. A. (2006). Histopathology of the lymph nodes. Toxicol Pathol 34, 425-54. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/17067938?dopt=Abstract)
Elmore, S., Lanning, L., Allison, N., Vallant, M., and Nyska, A. (2006). The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site. Toxicol Pathol34, 385-92. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/16844666?dopt=Abstract)
Zheng, C., Voutetakis, A., Kok, M. R., Goldsmith, C. M., Smith, G. B., Elmore, S., Nyska, A., Vallant, M., Irwin, R. D., and Baum, B. J. (2006). Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland. Oral Dis12, 137-44. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/16476034?dopt=Abstract)
Emmen, J.M., Couse, J.F., Elmore, S.A., Yates, M.M., Kissling, G.E., Korach, K.S. (2005). In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER){alpha} and ER{beta} null mice indicate a role for ER{beta} in follicular maturation. Endocrinology146(6), 2817-26. [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/15731357?dopt=Abstract)
Savolainen, S.M., Foley, J.F., Elmore, S.A. (2009). Histology atlas of the developing mouse heart with emphasis on E11.5 to E18.5. Toxicologic pathology37(4):395-414. [Abstract](http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19359541)