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Cellular & Molecular Pathology Branch

CMPB:  Cellular & Molecular Pathology Branch


To provide scientific collaboration of excellence to National Toxicology Program (NTP)  interdisciplinary research programs and DIR research using new technologies in biomedical research and to train pathology and lab animal fellows to be leaders in multidisciplinary research.



The Cellular and Molecular Pathology Branch (CMPB) conducts research on spontaneous and chemically induced lesions and the mechanisms by which they are induced. It also manages, evaluates, reviews and reports all pathology data generated during the conduct of the NTP toxicity and carcinogenicity studies. In addition, the CMPB maintains state-of the-science histology, electron microscopy, clinical pathology and special techniques core laboratories and provides diagnostic pathology support to all NIEHS investigators and the NIEHS laboratory animal colony.


CMPB is comprised of eight groups—led by Branch Chief Robert Sills, D.V.M., Ph.D., and provides the following services:


  • Develops and defines in vivo and in vitro models of experimental carcinogenesis and toxicology
  • Develops new methods and technologies in pathobiology
  • Establishes standards, terminology and diagnostic criteria for rodent pathology
  • Maintains the NTP archives and provides laboratory animal medicine support for the NTP
    • Core laboratory services including:
    • Hematology
    • Clinical chemistry
    • Histology
    • Immunohistochemistry (IHC)
    • Electron Microscopy (TEM)
    • Laser Microdissection
    • Phenotyping (Embryonic Lethality)
    • Digital Imaging/Analysis
    • Other Special Techniques – necropsy, frozen sections, & more

The Cellular & Molecular Pathology Branch is organized into seven workgroups:

Scientific Support Staff

Carolyn Hall
Administrative Specialist
Tel (919) 541-4995
Fax (301) 480-3116
Donna Roach
Administrative Technician
Tel (919) 541 3023
Sheila Withers
Tel (919) 541-5066

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