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National Institute of Environmental Health SciencesNational Institutes of Health

Scott S. Auerbach, Ph.D.

Host Susceptibility Branch

Scott S. Auerbach, Ph.D.
Scott S. Auerbach, Ph.D.
Molecular Toxicologist



Tel (919) 541-4505
Fax (919) 541-4255
auerbachs@niehs.nih.gov


Curriculum Vitae (http://www.niehs.nih.gov/research/atniehs/labs/hsb/staff/cunningham/docs/scott-auerbach-cv.pdf)  Download Adobe Reader (40 KB)
P.O. Box 12233
Mail Drop A2-12
Research Triangle Park, North Carolina 27709
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Scott S. Auerbach, Ph.D., is a Molecular Toxicologist in the Host Susceptibility Branch (HSB). He serves a dual role as a study scientist that designs and interprets guideline toxicity studies and as an experimentalist that seeks to understand variables that impact toxicity, such as species, genetics, disease state, nutrition, life stage and sex. In addition, Auerbach is interested in the development of genomic-based signatures derived from subchronic exposures that predict chronic toxicity and carcinogenicity.

Auerbach is currently involved in the creation of gene expression-based predictive models and the identification of genetic determinants of chemical-induced cardiotoxicity. He has spent a large fraction of his research career studying the molecular pharmacology of nuclear receptors, in particular with respect to their role in the regulation of hepatic gene expression. Auerbach was also trained in human genetics and was involved in the identification of genetic determinants of human pulmonary fibrosis.

As a member of the HSB, his goal is to identify causal relationships between molecular pathways and pathophysiological processes. Once these relationships are established he applies genomic and bioinformatics techniques to determine if the host variables listed above alter the function of disease-critical molecular pathways.

Auerbach received a B.S. in biochemistry and molecular biology from The Pennsylvania State University, State College, Pennsylvania and a Ph.D. in pharmacology from the University of Washington, Seattle, Washington.

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Last Reviewed: October 01, 2009