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Dana B. Hancock, Ph.D.

Genetics, Environment & Respiratory Disease Group

Dana B. Hancock, Ph.D.
Dana B. Hancock, Ph.D.
Special Volunteer
Tel (919) 316-4506
Fax (919) 541-2511
hancockd@niehs.nih.gov
Curriculum Vitae (22KB)
P.O. Box 12233
Mail Drop A3-05
Research Triangle Park, North Carolina 27709
Delivery Instructions


Dana Hancock, Ph.D., joined the Epidemiology Branch as an IRTA postdoctoral fellow in May 2008 shortly after completing her doctoral research from Duke University.  As a genetic epidemiologist, Hancock is interested in the interplay of genetic and environmental risk factors leading to common, complex diseases.  Her doctoral training focused on interactions between candidate genes and environmental factors in Parkinson’s disease. Her postdoctoral training with Stephanie London, M.D., Dr.P.H., focuses on genetic risk factors on a genome-wide scale and corresponding gene-environment interactions in respiratory diseases, including asthma and chronic obstructive pulmonary disease. In doing so, well-known environmental factors for respiratory disease, such as cigarette smoking and air pollution, are considered. Hancock is particularly interested in the use of family-based samples to explore gene-environment interactions in such complex diseases.

Studies

  • Mexico Childhood Asthma Study
    The Mexico Childhood Asthma Study is a case-parent triad study of childhood allergic asthma in Mexico City

  • The Atherosclerosis Risk in Communities (ARIC) Study The ARIC Study is a prospective epidemiologic study conducted in four U.S. communities. ARIC is designed to investigate the etiology and natural history of atherosclerosis, the etiology of clinical atherosclerotic diseases and variation in cardiovascular risk factors.

Selected Publications

  1. Hancock DB, Haberg SE, Furu K, Whitworth KW, Nafstad P, Nystad W, London SJ. Oral contraceptive pill use before pregnancy and respiratory outcomes in early childhood. Pediatric allergy and immunology 22(5):528-536, 2011. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=21294776) ]
  2. Shi M, London SJ, Chiu GY, Hancock DB, Zaykin D, Weinberg CR. Using imputed genotypes for relative risk estimation in case-parent studies. American journal of epidemiology 173(5):553-559, 2011. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=%2021296892) ]
  3. Hancock DB, London SJ, CHARGE Pulmonary Function Working Group. Determinants of lung function, COPD, and asthma. The New England journal of medicine. 364(1):86-87, 2011. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=21208119) ]
  4. Aschard H, Hancock DB, London SJ, Kraft P. Genome wide meta-analysis of joint tests for genetic and gene-environment interaction effects. Human heredity. 70(4):292-300, 2010. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=21293137) ]
  5. Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YMTA, Chen T, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter J, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BHC, O'Connor GT, London SJ. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nature genetics. 42(1):45-52, 2010. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=20010835) ]
  6. Wu H, Romieu I, Shi M, Hancock DB, Li H, Sienra-Monge JJ, Chiu GY, del Rio-Navarro BE, London SJ. Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans. The Journal of allergy and clinical immunology. 125(2):321-327, 2010. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19910030) ]
  7. Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YMTA, Chen T, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter J, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BHC, O'Connor GT, London SJ. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nature genetics. 42(1):45-52, 2010. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=20010835) ]
  8. Wu H, Romieu I, Shi M, Hancock DB, Li H, Sienra-Monge JJ, Chiu GY, del Rio-Navarro BE, London SJ. Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans. The Journal of allergy and clinical immunology. 125(2):321-327, 2010. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19910030) ]
  9. Hancock DB, Romieu I, Shi M, Sienra-Monge JJ, Wu H, Chiu GY, Li H, del Rio-Navarro BE, Eng C, Chapela R, Burchard EG, Tang H, Sullivan PF, London SJ. Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children. PLoS genetics. 5(8):e1000623, 2009. [Abstract (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=19714205) ]
  10. Hancock DB, Martin ER, Vance JM, Scott WK (2008). Nitric oxide synthase genes and their interactions with environmental factors in Parkinson's disease. Neurogenetics 9(4):249-262.
  11. Hancock DB, Martin ER, Mayhew GM, Stajich JM, Jewett R, Stacy MA, Scott BL, Vance JM, Scott WK (2008). Pesticide exposure and risk of Parkinson's disease: a family-based case-control study. BioMed Central Neurology 8(6). [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18373838?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) ]
  12. Hancock DB, Martin ER, Li YJ, Scott WK (2007). Methods for interaction analyses using family-based case-control data: conditional logistic regression versus generalized estimating equations. Genetic Epidemiology 31(8):883-893.
  13. Hancock DB, Martin ER, Stajich JM, Jewett R, Stacy MA, Scott BL, Vance JM, Scott WK (2007). Smoking, caffeine, and nonsteroidal anti-inflammatory drugs as protective factors in families with Parkinson disease. Archives of Neurology 64(4):576-580. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17420321?ordinalpos=2&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) ]
  14. Hancock DB, Martin ER, Fujiwara K, Stacy MA, Scott BL, Stajich JM, Jewett R, Li YJ, Hauser MA, Vance JM, Scott WK (2006). NOS2A and the modulating effect of cigarette smoking in Parkinson’s disease. Annals of Neurology 60(3):366-373. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16823855?ordinalpos=3&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum) ]

 
Last Reviewed: August 18, 2011