Paul Dunlap is a biologist in the Biomolecular Screening Branch of the National Toxicology Program Division at the National Institute of Environmental Health Sciences (NIEHS). He participates in the study and data collection of the NTP WormTox Screening Facility.
Since 2006, Dunlap and the rest of the WormTox group have used the nematode Caenorhabditis elegans as an alternative model organism in high-throughput toxicological screening. Most recently, Dunlap has participated in studies comparing the toxicological effects of methyl mercury and inorganic mercury on a yeast deletion library using a high throughput robotic platform. More recently he has studied the effects of toxicants on mitochondrial function in living nematodes.
Dunlap received his B.A. in biology from Earlham College in Richmond, Indiana in 1986 and he completed graduate studies at the University of Colorado-Boulder in 2002. Before joining NIEHS in 2006, he worked in the laboratory of Jonathan Freedman, Ph.D. at Duke University's Integrated Toxicology Program.
- Jin YH, Dunlap PE, McBride SJ, Al-Refai H, Bushel PR, Freedman JH. Global transcriptome and deletome profiles of yeast exposed to transition metals. PLoS Genet. 2008 Apr 25;4(4):e1000053.
- Alper S, Laws R, Lackford B, Boyd WA, Dunlap P, Freedman JH, Schwartz DA. 2008. Identification of innate immunity genes and pathways using a comparative genomics approach. Proceedings of the National Academy of Sciences of the United States of America, 105(19):7061-7021. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18463287) ]