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Grace E. Kissling, Ph.D.

Biostatistics Branch

Grace Kissling, Ph.D.
Grace E. Kissling, Ph.D.
Staff Scientist
Tel (919) 541-1756
Fax (919) 541-4311
kissling@niehs.nih.gov
Curriculum Vitae (185KB)
P.O. Box 12233
Mail Drop A3-03
Research Triangle Park, North Carolina 27709
Delivery Instructions

 

Grace E. Kissling’s primary responsibilities involve providing statistical advice and assistance for the toxicology and carcinogenicity studies carried out by the National Toxicology Program and experimental studies carried out by NIEHS researchers. She collaborates on research at all stages: study design, statistical analysis and interpretation. She is also an adjunct member in the Host Susceptibility Branch.

Selected Publications

  1. Nwosu VC, Kissling GE, Trempus CS, Honeycutt H, French JE.  Exposure of Tg.AC transgenic mice to benzene suppresses hematopoietic progenitor cells and alters gene expression in critical signaling pathways. Toxicology and Applied Pharmacology 2004; 196(1):37-46. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15050406?dopt=Abstract) ]
  2. Ghanayem BI, Witt KL, El-Hadri L, Hoffler U, Kissling GE, Shelby MD, Bishop JB.  Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect. Biology of Reproduction 2005; 72:157-163. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15355880?dopt=Abstract) ]  
  3. Bebenik A, Carver GT, Kadyrov FA, Kissling GE, Drake JW.  Processivity clamp gp45 and ssDNA-binding-protein gp32 modulate the fidelity of bacteriophage RB69 DNA polymerase in a sequence-specific manner, sometimes enhancing and sometimes compromising accuracy.  Genetics 2005; 169:1815-1824. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15695359?dopt=Abstract) ]  
  4. Salo PM, Xia J, Johnson CA, Li Y, Kissling GE, Avol EL, Liu C, London SJ.  Respiratory symptoms in relation to residential coal burning and environmental tobacco smoke among early adolescents in Wuhan, China: a cross-sectional study. Environmental Health 2004; 3:14. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15585063?dopt=Abstract) ]  
  5. Nyska A, Yoshizawa K, Jokinen MP, Brix AE, Sells DM, Wyde ME, Orzech DP, Kissling GE, Walker NJ. Olfactory epithelial metaplasia and hyperplasia in female Harlan Sprague-Dawley rats following chronic treatment with polychlorinated biphenyls.  Toxicologic Pathology 2005; 33(3):371-377 [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15805076?dopt=Abstract) ]  
  6. Emmen JMA, Couse JF, Elmore SA, Yates MM, Kissling GE, Korach KS.  In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER)? and ER? null mice indicate a role for ER? in follicular maturation. Endocrinology, 2005; 146(6):2817-2826. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15731357?dopt=Abstract) ]  
  7. Chen Y, Kissling GE, Negishi M, Goldstein J.  The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.  Journal of Pharmacology and Experimental Therapeutics 2005; 314:1125-1133. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15919766?dopt=Abstract) ]  
  8. Ghanayem BI, Witt KL, Kissling GE, Tice RR, Recio L.  Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: Evidence consistent with a glycidamide-mediated effect.  Mutation Research 2005; 578:284-297. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/15982677?dopt=Abstract) ]  
  9. Yoshizawa K, Kissling GE, Johnson JA, Clayton NP, Flagler ND, Nyska A.  Chemical-induced atrial thrombosis in NTP rodent studies.Toxicologic pathology 2005; 33:517-532. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16048847?dopt=Abstract) ]
  10. Drake JW, Bebenek A, Kissling GE, Peddada S.  Clusters of mutations from transient hypermutability. Proceedings of the National Academy of Sciences 2005; 102:12849-12854. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16118275?dopt=Abstract) ]  
  11. Tam NNC, Nyska A, Maronpot RR, Kissling G, Lomnitski L, Suttie A, Bakshi S, Bergman M, Grossman S, Ho SM.  Differential attenuation of oxidative/nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants.  The Prostate 2006; 66:57-69. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16114064?dopt=Abstract) ]  
  12. Chan SSL, Santos JH, Meyer JN, Mandavilli BS, Cook Jr. DL, McCash CL, Kissling G, van Houten B, Copeland WC, Walker VE, Witt KL, Bishop JB.  Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.  Environmental and Molecular Mutagenesis 2006; in press. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16395692?dopt=Abstract) ]
  13. Peddada SD and Kissling GE.  Evaluation of a survival-adjusted quantal-response test for analysis of tumor incidence rates in animal carcinogenicity studies.  Environmental Health Perspectives 2006; 114:537-541. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16581542?dopt=Abstract) ]  
  14. Dunnick J, Blackshear P, Kissling G, Cunningham M, Parker J, Nyska A. Critical pathways in heart function:  Bis(2-chloroethoxy)methane-induced heart gene change in F344 rats.  Toxicologic Pathology 2006; 34:348-356. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16844662?dopt=Abstract) ]  
  15. Kissling GE, Bernheim NJ, Hawkins WE, Wolfe MJ, Jokinen MP, Smith CA, Herbert RA, Boorman GA. The utility of the guppy (Poecilia reticulata) and medaka (Oryzias latipes) in evaluation of chemicals for carcinogenicity. Toxicological Sciences 2006; 92:143-156. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16581948?dopt=Abstract) ]  
  16. Elliott L, Longnecker MP, Kissling GE, London SJ.  Volatile organic compounds and pulmonary function in the third national National Health and Nutrition Examination Survey, 1988-1994.  Environmental Health Perspectives 2006; 114:1210-1214. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16882527?dopt=Abstract) ]  
  17. Fortune JM, Welch CM, Kissling GE, Burgers PMJ, Kunkel TA. RPA and PCNA suppress formation of large deletion errors by yeast DNA polymerase delta.  Nucleic Acids Research 2006; 34: 4335-4341. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16936322?dopt=Abstract) ]  
  18. Clayton NP, Yoshizawa K, Kissling G, Burka LT, Chan P-C, Nyska A.  Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract.  Experimental and Toxicologic pathology 2007; 58(4):223-236. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17059882?dopt=Abstract) ]  
  19. Zhong X, Garg P, Stith C, Nick-McElhinny S, Kissling G, Burgers P, Kunkel T. The fidelity of DNA synthesis by yeast DNA polymerase zeta alone and with accessory proteins.  Nucleic Acids Research 2006; 34: 4731-4742. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16971464?dopt=Abstract) ]  
  20. Elangbam CS, Wehe JG, Barton JC, Krull DL, Nyska A, Crabbs T, Kissling GE.  Evaluation of glycosaminoglycans content and 5-hydroxytryptamine 2B receptor in the heart valves of Sprague-Dawley rats with spontaneous mitral valvulopathy--a possible exacerbation by dl-amphetamine sulfate in Fischer 344 rats? Experimental and Toxicologic pathology 2006; 58: 89-99. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16996724?dopt=Abstract) ]  
  21. Peddada SD, Dinse GE, Kissling GE. Incorporating historical control data when comparing tumor incidence rates. Journal of the American Statistical Association 2007; 102(480):1212-1220. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20396669) ]  
  22. Kissling GE, Malarkey DE, Vallant MK, Johnson JD, Hejtmancik MR, Herbert RA, Boorman GA. Evaluation of dichloroacetic acid for carcinogenicity in genetically modified Tg.AC and p53 haploinsufficient mice.  Toxicological Sciences 2009; 107(1):19-26. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18974089) ]  
  23. Dumsdorf C, Clark AB, Lin Q, Kissling GE, Yuan T, Kunkel TA, McGregor WG, Kucherlapati R.  Participation of mouse DNA polymerase iota in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer.  Proceedings of the National Academy of Sciences 2006; 103(48):18083-18088. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17114294) ]  
  24. Moore AB, Flake GP, Swartz CD, Heartwell G, Cousins D, Haseman JK, Kissling GE, Sidawy MK, Dixon D.  Association of race, age and body mass index with gross pathology of uterine fibroids. Journal of Reproductive Medicine 2008; 53(2):90-96. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18357799) ]  
  25. Golumb E, Houminer E, Dunnick J, Kissling G, Borman J, Nyska A, Schwalb H. Occult cardiotoxicity: Subtoxic dosage of bis(2-chloroethoxy)methane impairs cardiac response to simulated ischemic injury.  Toxicologic pathology 2007; 35(3):383-387. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17455086) ]  
  26. Witt KL, Cunningham CK, Patterson KB, Kissling GE, Dertinger SD, Livingston E, Bishop JB.  Elevated frequencies of micronucleated erythrocytes in infants exposed to zidovudine in utero and postpartum to prevent mother-to-child transmission of HIV.  Environmental and Molecular Mutagenesis  2007; 48(3-4):322-329. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17358032) ]  
  27. Kissling GE, Dertinger S, Hayashi M, MacGregor JT. Sensitivity of the Erythrocyte Micronucleus Assay: Dependence on number of cells scored and inter-animal variability. Mutation research 2007; 1-2:235-240. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17851117?dopt=Abstract) ]  
  28. Kissling GE, Malarkey DE, Vallant MK, Johnson JD, Hejtmancik MR, Herbert RA, Boorman GA. Evaluation of dichloroacetic acid for carcinogenicity in genetically modified Tg.AC hemizygous and p53 haploinsufficient mice. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 2006; 2-3: 89-99. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/16996724?dopt=Abstract) ]  
  29. Jiang C, Foley J, Clayton N, Kissling G, Jokinen M, Herbert R, Diaz M. Abrogation of lupus nephritis in activation-induced deaminase-deficient MRL/lpr Mice. Journal of Immunology (Baltimore, Md. : 1950) 2007; 11:7422-7431. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17513793?dopt=Abstract) ]  
  30. Melnick RL, Nyska A, Foster PM, Roycroft JH, Kissling GE. Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and mice. Toxicology 2007; 2-3:126-136. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17157429?dopt=Abstract) ]  
  31. Bennett WD , Hazucha MJ, Folinsbee LJ, Bromberg PA, Kissling GE, London SJ. Acute pulmonary function response to ozone(O3) in young adults as a function of body mass index (BMI). Inhalation toxicology 2007; 19(14):1147-1154. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17987466?dopt=Abstract) ]  
  32. Stout MD, Herbert RA, Kissling GE, Suarez F, Roycroft JH, Chhabra RS, Bucher JR. Toxicity and carcinogenicity of methyl isobutyl ketone in F344N rats and B6C3F1 mice following two year inhalation exposure. Toxicology 2008; 244(2):209-219. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18178301?dopt=Abstract) ]  
  33. Thigpen JE, Setchell KDR, Haseman JK, Saunders HE, Caviness GF, Kissling GE, Grant MG, Forsythe DB. Variations in phytoestrogen content between different mill dates of the same diet produces significant differences in the time of vaginal opening in CD-1 mice and F344 rats but not in CD Sprague Dawley rats. Environmental health perspectives 2007; 115(12):1717-1726. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18087589?dopt=Abstract) ]  
  34. Witt KL, Livanos E, Kissling GE, Torous DK, Caspary W, Tice RR, Recio L. Comparison of flow cytometry and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals. Mutation research 2008; 649(1-2):101-113. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17869571?dopt=Abstract) ]  
  35. Kissling GE, Portier CJ, Huff J. MtBE and cancer in animals: statistical issues with poly-3 survival adjustments for lifetime studies. Regulatory toxicology and pharmacology : RTP 2008; 50(3):428-429. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/17905498?dopt=Abstract) ]  
  36. Longnecker MP, Smith CS, Kissling GE, Hoppin JA, Butenhoff JL, Decker E, Ehresman DJ, Ellefson ME, Flaherty J, Gardner MS, Langlois E, LeBlanc A, Lindstrom AB, Reagen WK, Strynar MJ, Studabaker WB. An interlaboratory study of perfluorinated alkyl compound levels in human plasma. Environmental Science and Technology 2008; 107(2):152-159. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18295197?dopt=Abstract) ]  
  37. Hard GC, Seely JC, Kissling GE, Betz LJ. Spontaneous occurrence of a distinctive renal tubule tumor phenotype in rat carcinogenicity studies conducted by the National Toxicology Program (NTP). Toxicologic pathology 2008; 36(3):388-396. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18441261?dopt=Abstract) ]  
  38. Stout MD, Kissling GE, Suárez FA, Malarkey DE, Herbert RA, Bucher JR. Influence of helicobacter hepaticus infection and diet on the chronic toxicity and carcinogenicity of triethanolamine in B6C3F1 mice. Toxicologic pathology 2008; 36(6):783-794. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/18812577?dopt=Abstract) ]  
  39. Stout MD, Nyska A, Collins BJ, Witt KL, Kissling GE, Malarkey DE, Hooth MJ. Chronic toxicity and carcinogenicity studies of chromium picolinate monohydrate administered in feed to F344/N rats and B6C3F1 mice for 2 years. Food and chemical toxicology 2009; 47(4):729-733. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19166900?dopt=Abstract) ]  
  40. Cullen JM, Brown DL, Kissling GE, Foley JF, Rizzo J, Marion PL, Parron VI, French JE. Aflatoxin B1 and/or hepatitis B virus induced tumor spectrum in a genetically engineered hepatitis B virus expression and Trp53 haploinsufficient mouse model system for hepatocarcinogenesis. Toxicologic pathology 2009; 37():1-10. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19258306?dopt=Abstract) ]  
  41. Schindler EM, Hindes A, Gribben EL, Yin Y, Lin MH, Owen RJ, Longmore GD, Kissling GE, Arhtur JS, Efimova T. p38d Mitogen-activated protein kinase is essential for skin tumor development in mice. Cancer research 2009; 69(11):4648-4655. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19458068?dopt=Abstract) ]  
  42. Ramot Y, Nyska A, Lieuallen W, Maly A, Flake G, Kissling G, Brix A, Malarkey D, Hooth M. Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to tetrachloroazobenzene (TCAB) for 2 years. Toxicology 2009; 265(1-2):1-9. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19737593?dopt=Abstract) ]  
  43. Hewitt SC , O'Brien J , Jameson L, Kissling G , Korach KS. Selective disruption of ER{alpha} DNA-binding activity alters uterine responsiveness to estradiol. Molecular endocrinology (Baltimore, Md.) 2009; 23(12):2111-2116. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19812388?dopt=Abstract) ]  
  44. Cannon CZ, Kissling G, Hoenerhoff MJ, King-Herbert A, Blankenship-Paris T. Evaluation of dosages and routes of administration of tramadol analgesia in rats using hot-plate and tail-flick tests. Lab animal 2010; 39(11):342-351. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20962760?dopt=Abstract) ]  
  45. Hewitt SC, Kissling GE, Fieselman KE, Jayes FL, Gerrish KE, Korach KS. Biological and biochemical consequences of global deletion of exon 3 from the ER{alpha} gene. The FASEB journal 2010; 24(12):4660-4667 [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20667977?dopt=Abstract) ]  
  46. Blystone CR, Kissling GE, Bishop JB, Chapin RE, Wolfe GW, Foster PMD. Determination of the di-(2-ethylhexyl) phthalate (HEHP) NOAEL for reproductive development in the rat: importance of the retention of extra animals to adulthood. Toxicological Sciences 2010; 116(2):640-646. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20484383?dopt=Abstract) ]  
  47. Boyd WA, Smith MV, Kissling GE, Freedman JH. Medium and high throughput screening of neurotoxicants using C. elegans. Neurotoxicology and Teratology 2010; 32:68-73. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19166924) ]  
  48. Chan P-C, Ramot Y, Malarkey DE, Blackshear P, Kissling GE, Travlos G, Nyska A. Fourteen-week toxicity study of green tea extract in rats and mice. Toxicologic pathology 2010; 38(7):1070-1084. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20884815) ]  
  49. Collins BJ, Stout MD, Levine KE, Kissling GE, Fennell T, Pritchard J, Fernando R, Burka LT, Hooth MJ. Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared to trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice. Toxicological Sciences 2010; 118:368-379. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20843897) ]  
  50. Ding H, Zhang L, Wu B, Wang Q, Hui R, Wang W, Dackor RT, Kissling GE, Zeldin DC, Wang DW. Association of common variants of CYP4A11 and CYP4F2 with stroke in the Chinese Han population. Pharmacogenetics and Genomics 2010; 20:187-194. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20130494) ]  
  51. Ghanayem BI, Bai R, Kissling GE, Travlos G, Hoffler U. Diet-induced obesity in male mice is associated with reduced fertility and potentiation of acrylamide-induced reproductive toxicity. Biology of Reproduction 2010; 82:96-104. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19696015) ]  
  52. Kim YS, Harry GJ, Kang HS, Goulding D, Wine R, Kissling GE, Liao G, Jetten AM. Altered Cerebellar Development in Nuclear Receptor TAK1/TR4 Null Mice is Associated with Deficits in GLAST(+) Glia, Alterations in Social Behavior, Motor Learning, Startle Reactivity, and Microglia. Cerebellum (London, England) 2010; 9(3):310-323. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20393820?dopt=Abstract) ]  
  53. Moore AB, Yu L, Swartz CD, Zheng X, Wang L, Castro L, Kissling GE, Walmer DK, Robboy SJ, Dixon D. Human uterine leiomyoma-derived fibroblasts stimulate uterine leiomyoma cell proliferation and collagen type I production with activation of RTKs and TGF beta receptor signaling in coculture. Cell Communication and Signaling 2010, 8:10. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20537183) ]  
  54. Nick McElhinney SA, Kissling GE, Kunkel TA. Differential correction of lagging strand replication errors made by DNA polymerases alpha and delta. Proceedings of the National Academy of Sciences 2010; 107(49):21070-21075. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21041657) ]  
  55. Poltoratsky V, Heacock M, Kissling GE, Prasad R, Wilson SH. Mutagenesis dependent upon the combination of activation-induced deaminase expression and a double-strand break. Molecular Immunology 2010; 48:164-170. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20828826) ]  
  56. Rana R, Chen Y, Ferguson S, Kissling GE, Surapureddi S, Goldstein JA. Hepatocyte nuclear factor 4α regulates rifampicin-mediated induction of CYP2C genes in primary cultures of human hepatocytes. Drug Metabolism and Disposition 2010; 38:591-599. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20086032) ]  
  57. Singh BP, Nyska A, Kissling GE, Lieuallen W, Johansson SL, Malarkey DE, Hooth MJ. Urethral carcinoma and hyperplasia in male and female B6C3F1 mice treated with 3,3',4,4'-tetrachloroazobenzene (TCAB). Toxicologic pathology 2010; 38(3):372-381. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20233943?dopt=Abstract) ]  
  58. Travlos GS, Hard GC, Betz L, Kissling GE. Chronic progressive nephropathy in male F344 rats in 90-day toxicity studies: its occurrence, and association with renal tubule tumors in subsequent 2-year bioassays. Toxicologic pathology 2010; in press.  
  59. Tubbs JT, Kissling GE, Travlos GS, Goulding D, Clark J, King-Herbert AP. The effects of buprenorphine, meloxicam, and flunixin meglumine as post-operative analgesia in mice. Journal of the American Association for Laboratory Animal Science 2010; in press.  
  60. Whiteside TE, Thigpen JE, Kissling GE, Grant MG, Forsythe DB. Endotoxin, coliforms and dust levels in various types of rodent bedding. Journal of the American Association for Animal Laboratory Science 2010; 49:184-189. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20353693) ]  
  61. Witt KL, Malarkey DE, Hobb CA, Davis JP, Kissling GE, Caspary W, Travlos G, Recio L. No increases in biomarkers of genetic damage or pathological changes in heart and brain tissues in male rats administered methylphenidate hydrochloride (Ritalin) for 28 days. Environmental and molecular mutagenesis 2010; 51(1):80-88. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/19634155?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5) ]  
  62. Yoshizawa K, Walker NJ, Kissling GE, Jokinen MP, Brix AE, Sells DM, Nyska A., Wyde ME. Thyroid follicular lesions induced by oral treatment for two years with 2,3,7,8-tetrachlorodi-benzo-p-dioxin and dioxin-like compounds in female Harlan Sprague-Dawley rats. Toxicologic pathology 2010; 38(7):1037-1050. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/20924081) ]  
  63. Brodie B, Pokharel Y, Fleishman N, Bensimhon A, Kissling G, Hansen C, Milks S, Cooper M, McAlhany C, Stuckey T. Very late stent thrombosis after primary percutaneous coronary intervention with bare metal stents and drug-eluting stents for ST-elevation myocardial infarction: A 15 year single-center experience. JACC. Cardiovascular interventions 2011; 4(1):30-38. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21251626?dopt=Abstract) ]  
  64. Collins BJ, Stout MD, Levine KE, Kissling GE, Melnick RL, Fennell TR, Abdo K, Pritchard JB, Walden R, Fernando RA, Burka LT, Hooth MJ. Hexavalent chromium in drinking water, reply. Toxicological Sciences 2011; 119(2):425. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21081757?dopt=Abstract) ]  
  65. Cannon CZ, Kissling GE, Goulding DR, King-Herbert AP, Blankenship-Paris T. Comparison of Analgesia Effects of Tramadol, Carprofen, or Multimodal Analgesia in Rats Undergoing Ventral Laparotomy. Lab animal 2011; 40(3):85-93. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21326189?dopt=Abstract) ]  
  66. Hill GD, Moore AB , Kissling GE , Flagler ND , Ney E, Cline JM , Dixon D. Effects of Hormonally Active Agents on Steroid Hormone Receptor Expression and Cell Proliferation in the Myometrium of Ovariectomized Macaques. Toxicologic pathology 2011; 39(3):508-515. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21411722?dopt=Abstract) ]  
  67. Dunnick JK, Singh B, Nyska A, Peckham J, Kissling GE, Sanders JM. Investigating the potential for toxicity from long-term use of the herbal products, Goldenseal and Milk thistle. Toxicologic pathology 2011; 39(2):398-409. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21300790?dopt=Abstract) ]  
  68. Tubbs JT, Kissling GE, Travlos GS, Goulding DR, Clark JA, King-Herbert AP, Blankenship-Paris TL. Effects of buprenorphine, meloxicam, and flunixin meglumine as postoperative analgesia in mice. Journal of the American association for laboratory animal science 2011; 50(2):185-191. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21439211?dopt=Abstract) ]  
  69. Clark AB, Lujan SA, Kissling GE, Kunkel TA. Mismatch repair-independent tandem repeat sequence instability resulting from ribonucleotide incorporation by DNA polymerase varepsilon. DNA repair 2011; 10(5):476-482. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21414850?dopt=Abstract) ]  
  70. Chan PC, Peckham JC, Malarkey DE, Kissling GE, Travlos GS, Fu PP. Two-Year Toxicity and Carcinogenicity Studies of Panax Ginseng in Fisher 344 Rats and B6C3F1 Mice. The American journal of Chinese medicine 2011; 39(4):779-788. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21721156?dopt=Abstract) ]  
  71. Bernstein DI, Kissling GE, Khurana Hershey G, Yucesoy B, Johnson VJ, Cartier A, Gautrin D, Sastre J, Boulet LP, Malo JL, Quirce S, Tarlo SM, Langmeyer S, Luster MI, Lummus ZL. Hexamethylene diisocyanate asthma is associated with genetic polymorphisms of CD14, IL-13, and IL-4 receptor alpha. Journal of Allergy and Clinical Immunology 2011; 128(2):418-420. [Abstract (http://www.ncbi.nlm.nih.gov/pubmed/21489615?dopt=Abstract) ]


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Last Reviewed: October 04, 2011