Licensing Opportunities
The inventions created in NIEHS laboratories may be transferred to the private sector for further research and development, and eventual commercialization through licenses. A company may acquire any of the following licenses:
- Unpatented Material
- Patented Material
- Patent-pending Material
- Commercial Evaluation
- Biological Materials
- Exclusive/Nonexclusive
The licensing application and negotiation process for institutes within the National Institutes of Health (NIH) is managed by the NIH Office of Technology Transfer .
NIEHS Technologies Available for Licensing & Collaborative Development
| CATEGORY | TITLE | KITS* CASE NO. |
|---|---|---|
| Antibody | Estrogen Receptor (ER) alpha P2 and P3, ER gamma Polyclonal Abs | ES-079 |
| Rabbit Antibodies to Mouse and Human Lactoferrin and C3 | ES-081 | |
| Mouse Monoclonal Antibody to Nitrone Spin Trap 5,5-dimethyl-1-pyrroline N-oxide (DMPO) | ES-086 | |
| Monoclonal Antibody to Human DNA Polymerase Beta | ES-100 | |
| Polyclonal Antibodies to Ser 134 Phosphorylated form of the Human Glucocorticoid Receptor | ES-107 | |
| Mouse Monoclonal Antibodies to Human Tristetraprolin (TTP) | ES-112 | |
| Monoclonal Antibodies Inhibitory to Human CYP2J2 | ES-116 | |
| Polyclonal Antibodies to Human CYP2J and CYP2C | ES-117 | |
| Antibody to pro-peptide of NSAID-activated Gene (NAG-1)/GDF-15 | ES-125 | |
| Cells | Chinese Hamster Ovary (CHO) Cells Expressing Retinoid Orphan Receptor (ROR)γ and Luciferase Reporter | ES-108 |
| Methods & Reagents | Transformation Associated Recombination System in Yeast for Specific Cloning of DNAs as Yeast Artificial Chromosomes | ES-017 |
| Rapid, Efficient In Vivo site-Directed Mutagenesis Using Oligonucleotides | ES-054 | |
| Mouse Lactoferrin | ES-081 | |
| An Efficient and Cost-Effective Assay for Genotyping Mice using Melting Curve Analysis | ES-114 | |
| Human CYP2J and CYP2C | ES-117 | |
| Purified Human DNA Polymerase G | ES-120 | |
| Fluorescent Intracellular Calcium Indicators | ES-124 | |
| Mouse Models | Estrogen Receptor (ER)-alpha & ER-beta KO Mice | ES-002 |
| Mouse Model for Early Onset Cataract | ES-066 | |
| Mouse Expressing Enhanced Signaling for Bone Morphogenetic Protein (BMP): A Model for Human Disease | ES-102 | |
| Knock-In mouse and Embryonic Stem Cells Expressing Leukemia Inhibitory Factor (LIF) | ES-109 | |
| Transgenic Mouse Expressing Human Nonsteroidal anti-inflammatory drug-activated Gene (NAG-1) | ES-110 | |
| Retinoid Orphan Receptor (ROR)γ Deficient Mice | ES-113 | |
| Mouse Strain with Conditional Deletion of SMAD7 gene | ES-115 | |
| Transgenic Mouse with Cre recombinase Expressed in Spermatogenic cells under Regulation of the Hspa2 Gene Promoter | ES-118 | |
| Heat-shock Protein A2 (Hspa2) Knock-out Mouse for Study of Spermatogenesis and Male Infertility | ES-119 | |
| GLI-Similar 3 (GLIS3) KO Mice and Mice in which GLIS3 is KO in Selective Tissues | ES-121 | |
| Therapeutics | Antagonists of Hyaluronan Signaling for Treatment of Airway inflammation and Hyperresponsiveness | ES-126 |
| Anti-inflammatory Actions of Cytochrome P450 Epoxygenase-Derived Eicosanoids | ES-039 | |
| Diagnostics and Therapeutics for Hydrocephalus | ES-064 | |
| Novel Methods for Reducing Inflammation and Treating Diseases such as Parkinson’s and Alzheimer’s Disease | ES-078 | |
| Target for Development of Diagnostics and Therapeutics for Abnormal Hematopoiesis | ES-095 | |
| Lrch4 - a Novel Regulator of Inflammation | ES-122 | |
| Functional Blockade of Inter-alpha-trypsin Inhibitor to Reduce Ariway Hyperreactivity in Environmental and Chronic Respiratory Diseases | ES-123 | |
* For description of these technologies please go to the KITS (Knowledge & Technology Sharing website). This website provides detailed information on NIEHS technologies and those of several other NIH Institutes. Contact the NIEHS-OTT for any additional information.
