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Nobel Winner Oliver Smithies to Give Rodbell Lecture April 14

By Eddy Ball
April 2009

Rodbell Lecturer Oliver Smithies
Rodbell Lecturer Oliver Smithies
(Photo courtesy of the University of North
Carolina at Chapel Hill)

Nobel Laureate Oliver Smithies, D.Phil., will deliver the eleventh annual Rodbell Lecture on April 14 at 2:00 p.m. in Rodbell Auditorium. Smithies' seminar, "Turning Pages: From Gels to Genes," is part of the NIEHS 2008-2009 Distinguished Lecture Series.

Smithies(http://www.pathology.unc.edu/common/smithies.htm) Exit NIEHS is an Excellence Professor in the Department of Pathology and Laboratory Medicine at the University of North Carolina at Chapel Hill School of Medicine. He has collaborated with NIEHS principal investigators on several studies related to genetic medicine and gene therapy.

In 2007, Smithies shared the Nobel Prize in Physiology or Medicine with Mario R. Capecchi, Ph.D., of the University of Utah's Howard Hughes Medical Institute and Sir Martin J. Evans, D.Sc., of Cardiff University in Wales. In its announcement(http://nobelprize.org/nobel_prizes/medicine/laureates/2007/press.html) Exit NIEHS of the prize, the Nobel Foundation praised the trio “for their discoveries of principles for introducing specific gene modifications in mice by the use of embryonic stem cells.” The scientists' work in the mid-1980s co-discovered a technique, gene targeting, to introduce DNA material in cells, replicating a natural process called homologous DNA recombination and establishing the basis for creating transgenic mice that replicate human disease.

Polypeptide Hormone Action Group Principal Investigator Perry Blackshear, M.D., D.Phil.(http://www.niehs.nih.gov/research/atniehs/labs/lst/polypeptide/index.cfm), will host the talk.



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