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Lefkowitz to Give Rodbell Lecture May 5

By Eddy Ball
May 2008

2008 Rodbell Lecturer Robert K. Lefkowitz, M.D.
2008 Rodbell Lecturer Robert K. Lefkowitz, M.D. (Photo courtesy of Robert Lefkowitz)

On May 5 from 2:00 to 3:00, Robert K. Lefkowitz, M.D., will deliver the tenth annual Rodbell Lecture on "Seven Transmembrane Receptors."

The James B. Duke Professor of Medicine and Biochemistry at Duke University, Lefkowitz also holds an appointment as an investigator with the Howard Hughes Medical Institute and is the winner of the 2007 Shaw Prize in Life Science and Medicine. His laboratory's work focuses on the elucidation of the molecular properties and regulatory mechanisms controlling the function of G protein-coupled receptors.

Lefkowitz and his colleagues have performed studies to discover the general principles of signal transduction from the outside to the inside of the cell involved in systems as diverse as sensory perception and neurotransmitter and hormonal signaling. His group is currently experimenting with novel approaches to the treatment of congestive heart failure in animal models, including the encoding of gene products that when expressed in the myocardium may markedly enhance cardiac contractility.

David Armstrong, Ph.D., acting chief of the NIEHS Laboratory of Neurobiology, will host the lecture.



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