Environmental Factor, November 2006, National Institute of Environmental Health Sciences
Party Time for Kids in Cincinnati Children's Study
By Eddy Ball
The Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS) concluded its five-year study of the role of diesel exhaust particles (DEP) and allergy on a fun note by throwing a picnic and party for participants. The October 7 event was held at the Cincinnati Zoo and featured activities and puppets. It was the study's way to thank participants and their parents and remind them to comply with treatment plans and attend follow-up visits.
Funded by an NIEHS grant administered through DERT, the study focused on children living in the Cincinnati metropolitan region, where three interstate corridors intersect creating one of the busiest U.S. north/south and east/west commercial truck routes converging on a population of 1.9 million. The conversion of the three interstates causes traffic volumes to be one of the largest in the country. Researchers sought to determine if infants who are exposed to DEP via truck exhaust are at an increased risk for atopy and atopic respiratory disorders. They also wanted to determine if this effect is magnified in a genetically at risk population. According to CCAAPS, results of this study may ultimately result in finding a preventable cause of atopic disorders in children.
According to Epidemiologist Grace LeMasters Ph.D., principal investigator of the study, CCAAPS has made significant progress in identifying genetic and environmental influences on atopy and atopic respiratory disorders during early childhood. The study has led to greater understanding of the pathophysiology and provided more insight into the development of preventative measures for these common childhood disorders.