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Panel Confirms Previous Findings on DEHP

By Colleen Chandler
November 2005

An expert panel convened Oct. 10-12 to review research on reproductive and developmental toxicity of DEHP a chemical commonly found in plastic, including building and car products, clothing, food packaging, children's products and some medical devices, concluded that not much has changed since a similar panel looked at the issues in 2000.

The Center for the Evaluation of Risks to Human Reproduction, part of the National Toxicology Program, convened the panel to review the estimated 150 papers that were published on human exposure and reproductive or developmental toxicity of di(2-ethylhexyl)phthalate since the first panel met in 2000.

The panel concluded:

  • For the general adult population, there is minimal concern of exposure
  • For healthy infants and toddlers, there is some concern that exposure can adversely impact reproductive development in males at least 1 year old, but there is concern that exposure can adversely affect reproductive development in infants less than 1 year old.
  • For critically ill infants, there is serious concern that certain exposure elevels may adversely affect male reproductive tract development.

The panel also concluded there is some concern for baby boys whose mothers were exposed to DEHP during pregnancy.

The panel was made up of 11 scientists, who looked at the quality, quantity and strength of the evidence, and identified data gaps and research needs. The final report will be available from the CERHR web page at http://cerhr.niehs.nih.gov/. Public comments will be solicited via the Federal register.



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