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(ICEM2005) Satellite Meeting: Toxicogenomics
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| MONDAY, AUGUST 29 | |
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| 2:00 – 6:00 pm | Arrival and Registration |
| 6:00 – 8:00 pm | Welcome Reception (Appetizers and Cash Bar) |
| TUESDAY, AUGUST 30 | |
| SESSION ONE: 9:00 AM – 12:00PM | |
| International Research Efforts in Toxicogenomics | |
| Discussion Leader: | |
| Uwe Heinrich, Fraunhofer ITEM, Germany Taisen Iguchi, National Institutes of Natural Sciences, Japan |
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| Speakers: | |
| 9:00 – 9:30 am | Raymond Tennant, NIEHS/NCT, USA Toxicogenomics and Health Research |
| 9:40 – 10:10 am | Tohru Inoue, NIHS, Japan Toxicogenomics Strategies and Current Discoveries |
| 10:20 – 10:40 am | Coffee Break |
| 10:40 – 11:10 am | Joost van Delft, Maastricht Univ., Netherlands Toxicogenomics Approaches in Studies on Gene-Environment Interactions Focusing on Carcinogenesis |
| 11:20 – 11:50 am | Michael Waters, NIEHS, USA Building a Toxicogenomics Knowledgebase |
| 12:00 – 1:00 pm | Lunch Break |
| 4:00 – 6:00 pm | POSTERS AND EXHIBITS–SESSION I –(Cash Bar) |
| Dinner On Your Own | |
| SESSION TWO–7:30 PM–9:30 PM | |
| Genomics and Disease Outcomes | |
| Discussion Leaders: | |
| Taku Nagao, NIHS, Japan, and Raymond W. Tennant, NIEHS/NCT, USA |
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| Speakers: | |
| 7:30 – 8:00 pm | Tatsuhiko Kodama, University of Tokyo, Japan Dynamic Systems Biology of Atherosclerosis |
| 8:10 – 8:40 pm | Tim Gant, University of Leicester, UK A Genomic Perspective of Liver Disease Resulting from Obesity, Cholestasis and Steatosis |
| 8:50 – 9:20 pm | Martyn Smith, University of California, USA Toxicogenomic Studies of Human Populations |
| WEDNESDAY, AUGUST 31 | |
| 8:30 am | Conference Photo |
| SESSION THREE – 9:00 AM – 12:00 NOON | |
| Collaborative Research in Consortia | |
| Discussion Leaders: | |
| Jos Kleinjans, Maastricht University, Netherlands, and Richard S. Paules, NIEHS/NCT, USA |
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| Speakers: | |
| 9:00 – 9:30 am | Cynthia Afshari, Amgen Inc., USA The ILSI Toxicogenomics Research Consortium – Working on the Hurdles |
| 9:40 – 10:10 am | Alex Merrick, NIEHS, USA ToxicoProteomics Biomarkers and Signatures of Acute Hepatic Injury |
| 10:20 – 10:40 am | Coffee Break |
| 10:40 – 11:10 am | Samir Hanash, Fred Hutchinson Cancer Research Center, USA HUPO Research Collaborations – Progress |
| 11:20 – 12:00 pm | Special Lecture: |
| Kenneth Buetow, NCICB, USA Clinical Research and Bioinformatics at the NCI–Progress |
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| 12:00 – 1:00 pm | Lunch Break |
| 4:00 – 6:00 pm | POSTERS AND EXHIBITS–SESSION II – (Cash Bar) |
| Dinner On Your Own | |
| SESSION FOUR – 7:30 – 9:30 PM | |
| How Will Toxicogenomics Direct Us to the Molecular Etiology of Disease | |
| Discussion Leaders: | |
| Kenneth Ramos, Texas A&M University, USA, and Tohru Inoue, NIHS, Japan |
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| Speakers: | |
| 7:30 – 8:00 pm | George Orphanides, Syngenta, Inc., UK Molecular Response to Estrogens: Genes, Pathways and Molecular Cascades |
| 8:10 – 8:40 pm | Rick Paules, NIEHS, USA Transcriptomics and Pharmacogenomics/Toxicogenomics |
| 8:50 – 9:20 pm | Juergen Borlak, Fraunhofer ITEM, Germany Transcription Factors in Toxicogenomics |
| THURSDAY, SEPTEMBER 1 | |
| SESSION FIVE – 9:00 – 12:00 AM | |
| Databases, Data Integration, and Model Systems | |
| Discussion Leaders: | |
| John Weinstein, NCI, USA, and Cindy Afshari, Amgen, Inc., USA |
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| Speakers: | |
| 9:00 – 9:30 am | Susanna Sansone, EMBL–EBI, UK EBI Databases and Tools: Extracting Meaning from Microarrays |
| 9:40 – 10:10 am | Yvonne Dragan, NCTR, USA Integrating Toxicology and ‘Omics Datasets |
| 10:20 – 10:40 am | Coffee Break |
| 10:40 – 11:10 am | Martin Ringwald, Jackson Laboratory, USA Mouse Genome Informatics |
| 11:00 – 11:10 am | Discussion |
| 11:20 – 11:50 am | Howard Jacob, University of Wisconsin Medical College, USA The Rat Genome Database and Rat Model Systems for Pharmacological and Toxicological Research |
| 12:00 – 1:00 pm | Lunch Break |
| SESSION SIX – 1:30 – 5:00 PM | |
| Molecular Mechanisms of Action | |
| Discussion Leaders: | |
| Juergen Borlak, Fraunhofer ITEM, Germany, and Roger Ulrich, Merck, Inc., USA |
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| Speakers: | |
| 1:30 – 2:00 pm | Jun Kanno, NIHS Expression Profiling in Mechanistic Toxicology |
| 2:10 – 2:40 pm | John Weinstein, NCI, USA Integromics and Mechanistic Understanding |
| 2:50 – 3:10 pm | Coffee Break |
| 3:10 – 3:40 pm | Jenny Xiao, Agilent Technologies, Inc., USA Microarray and Proteomics Data Integration Using Informatics Tools -- A System Biology Approach |
| 3:45 – 4:15 pm | Yaron Turpaz, Affymetix, Inc., USA Expression Data Analysis Approaches to Identify Interspecies Concordance of Carcinogens Mechanisms |
| 4:20 – 5:00 pm | Special Lecture: |
| Yusuke Nakamura, University of Tokyo, Japan Human Genome Analysis |
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| 6:00 – 8:00 pm | Farewell Dinner (Cash Bar) |
| FRIDAY, SEPTEMBER 2 | |
| SESSION SEVEN – 9:00 – 11:45 AM | |
| Toxicogenomics and Pharmaceutical Safety Evaluation | |
| Discussion Leaders: | |
| Daniel Casciano, NCTR, USA, and Samir Hanash, Fred Hutchinson Cancer Research Center, USA |
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| Speakers: | |
| 9:00 – 9:30 am | Jiri Aubrecht, Pfizer, USA Toxicogenomic Analysis: and Emerging Approach for Risk Assessment in Drug Development |
| 9:40 – 10:10 am | Roger Ulrich, Rosetta Inpharmatics, Inc., USA Molecular Pro?ling of Drug Effects in Laboratory Animals and Humans |
| 10:20 – 10:40 am | CoffeeBreak |
| 10:40 – 11:10 am | Kenneth Ramos, University of Louisville, USA A Genomics Approach to Understand Underlying Biology and Pathogenetic Mechanisms of Environmental Injury |
| 11:30 – 11:45 am | Closing Remarks – Meeting Chairs |
| 12:00 – 1:00 pm | Lunch Break |
| DEPART | |