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Addiction & Chemical IntoleranceNIEHS Conference - September 19 & 20, 2005
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| MONDAY, SEPTEMBER 19 | |
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| INTRODUCTION | |
| 8:30 am | Samuel Wilson, Deputy Director, National Institute of Environmental Health Sciences (NIEHS/NIH), Research Triangle Park, NC |
| Welcome and Workshop Goals | |
| FEATURED SPEAKER | |
| 8:45 am | Ting-Kai Li, Director, National Institute on Alcohol Abuse and Alcoholism (NIAAA/NIH), Bethesda, MD |
| Alcohol Tolerance and Intolerance | |
| TOXICANT-INDUCED LOSS OF TOLERANCE | |
| 9:20 am | Claudia Miller, University of Texas Health Science Center at San Antonio, San Antonio, TX |
| Chemical Intolerance (Abdiction) and Addiction: Mirror Images? | |
| ENVIRONMENTAL EXPOSURES | |
| 9:45 am | Richard Corsi, University of Texas, Austin, TX |
| Human Exposure to Volatile Organic Compounds in Indoor Environments | |
| 10:10 am | Robin Whyatt, Columbia University Medical Center, New York City, NY |
| Pesticides: Assessing Exposures and Health Risks | |
| 10:35 am | Break |
| CLINICAL OBSERVATIONS AND PARALLELS | |
| 10:50 am | William Meggs, Brody School of Medicine at East Carolina University, Greensville, NC |
| Chemical Intolerance and Addiction: The Longest Five Days | |
| 11:15 am | Iris Bell, University of Arizona College of Medicine, Tucson, AZ |
| Individual Differences in Time-Dependent Sensitization: | |
| Possible Links between Environmentally-Triggered Illnesses and Addiction | |
| 11:40 am | Roland Griffiths, Johns Hopkins University, Baltimore, MD |
| Caffeine Dependence and Withdrawal | |
| 12:05 pm | Lunch |
| 1:00 pm | Mark Gold, University of Florida McKnight Brain Institute, Gainesville, FL |
| Occupational Exposures and Drug Addiction | |
| 1:25 pm | Robert Malcolm, Medical University of South Carolina Institute of Psychiatry, Charleston, SC |
| Consequences of Repeated Alcohol Detoxifications: | |
| New Findings with Anticonvulsants to Treat Withdrawal Syndrome | |
| 1:50 pm | Discussion |
| ANIMAL MODELS | |
| 2:15 pm | George Breese, University of North Carolina School of Medicine, Bowles Center for Alcohol Studies, Chapel Hill, NC |
| Multiple Ethanol Withdrawals: A "Kindling"/Stress Hypothesis of Alcoholism | |
| 2:40 pm | Terry Robinson, University of Michigan, Ann Arbor, MI |
| Persistent Effects of Psychostimulant Drugs on Brain and Behavior | |
| 3:05 pm | Break |
| 3:20 pm | Scott Bowen, Wayne State University, Detroit, MI |
| Abuse of Inhalants: Implications for Chemical Intolerance | |
| 3:45 pm | Barbara Sorg**, Washington State University College of Veterinary Medicine, Pullman, WA |
| Animal Model for Chemical Intolerance Using Low-level Formaldehyde and Pesticide Exposures | |
| 4:10 pm | David Overstreet**, University of North Carolina at Chapel Hill, Bowles Center for Alcohol Studies, Chapel Hill, NC |
| Animal Model of Chemical Intolerance with Underlying Cholinergic Hypersensitivity | |
| 4:35 pm | Discussion |
| 5:00 pm | Reception |
* Conference Chair
** Conference Co-chair
| TUESDAY, SEPTEMBER 20 | |
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| GENETICS/GENOMICS/PROTEOMICS | |
| 8:30 am | Cornelia Baines and Gail McKeown-Eyssen, University of Toronto, ON, Canada |
| Case-control Study of Genotypes Associated with Chemical Intolerance: | |
| CYP2D6, NAT1, NAT2, PON1, PON2 and MTHFR | |
| 8:55 am | Tamara Phillips, Oregon Health & Science University, Portland, OR |
| Addiction Genetics: Narrowing the Candidates | |
| 9:20 am | Kent Vrana, Penn State University, Hershey, PA |
| Genomics/Proteomics of Alcohol Responses | |
| 9:45 am | William Slikker, U.S. Food and Drug Administration, Jefferson, AR |
| Understanding the Role of Polymorphisms and Gene Expression in Drug Addiction: A Systems Biology Approach | |
| 10:10 am | Discussion |
| 10:30 am | Break |
| NEUROINFORMATICS | |
| 10:45 am | Leonid Bunegin, University of Texas Health Science Center at San Antonio, San Antonio, TX |
| Cerebral Blood Flow in Addiction, Withdrawal, and Chemical Intolerance | |
| 11:10 am | Howard Hu, Harvard University School of Public Health, Boston, MA |
| SPECT Scans and Chemical Intolerance | |
| 11:35 am | Marc Potenza, Yale University School of Medicine, New Haven, CT |
| Common Neural Correlates Across Addictions | |
| 12:00 pm | Discussion |
| 12:20 pm | Summation and Future Directions |
| 1:00 pm | Adjournment |
* Conference Chair
** Conference Co-chair
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