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NIEHS and NTP at the Society of Toxicology - 2013 Annual Meeting

San Antonio, TX
March 10-14, 2013

SOT 2013 San Antonio, TX

Schedule days:


Daylight Savings Time

Daylight Savings Time: Begins on Sunday, March 10, 2013 at 2:00AM. Please remember to turn your clock/watch forward one hour before going to bed to ensure you arrive on time for Sunday events!

NIEHS and NTP at the Society of Toxicology - 2013 Annual Meeting(372KB)

 

NIEHS, NTP, and EHP Exhibit

Booth 1218/1217/1117

Monday, March 11, 8:30 AM - 4:30 PM

  • NTP CEBS Demonstration: 2:00 PM - 4:00 PM

Tuesday, March 12, 8:30 AM - 4:30 PM

  • NTP CEBS Demonstration: 10:00 AM - 12:00 PM
  • NTP DrugMatrix: 2:00 PM – 4:00 PM

Wednesday, March 13, 8:30 AM - 4:30 PM

  • NTP Meta Data Viewer Graphing Demonstration: 9:00 AM - 11:00 AM & 12:00 PM - 2:00 PM
  • NTP CEBS Demonstration: 2:00 PM - 4:00 PM

 

Special Symposium: Meet the Directors

Grand Ballroom C1 (CC)

Monday, March 11, 1:00 PM - 3:30 PM

 

Exhibitor Hosted Session: National Toxicology Program
Implementing Systematic Review at the NTP

Room 0007B (CC)

Tuesday, March 12, 2:45 PM – 3:45 PM

Sunday, March 10

Toxic Effects of Metals

8:15 AM - 12:00 PM, Room 217 C&D (CC), Continuing Education, Chair M P Waalkes

  • Abstract #7
    Toxic Effects of Metals (M F Hughes, M P Waalkes)
    Metals in Carcinogenesis & Developmental Origins of Adult Disorders (E J Tokar)

Gonadal Development, Function, and Toxicology

1:15 PM - 5:00 PM, Room 217 A&B (CC), Continuing Education, Chair B McIntyre

  • Abstract #9
    Gonadal Development, Function, and Toxicology (B McIntyre, J A Flaws)

Undergraduate Education Program: Career Opportunities in Toxicology

2:00 PM - 3:15 PM, Grand Ballroom K (Marriott Rivercenter), Lecture


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Monday, March 11

Advances in Neurobehavioral and Neuropathology Assessment of Chemicals

9:15 AM - 12:00 PM, Room 205 (CC), Platform Session, Speaker M Behl

  • Abstract #53
    Perinatal Toxicity and Carcinogenicity Studies of Styrene Acrylonitrile Trimer, a Ground Water Contaminant (M Behl, S A Elmore, M R Hejtmancik, D K Gerken, R S Chhabra)

Genetic and Epigenetic Determinants of Susceptibility to Environmental and Occupational Toxicants

9:15 AM - 12:00 PM, Grand Ballroom C1 (CC), Symposium Session

  • Abstract #17
    Integrated Genetic and Genomic Approaches to Understand Susceptibility to Toxicant-Induced Lung Disease (S R Kleeberger)

Translatable Indicators of Testicular Toxicity: Inhibin B, microRNAs, and Sperm Signatures

9:15 AM - 12:00 PM, Room 214 C&D (CC), Symposium Session, Speaker B McIntyre

  • Abstract #25
    Translatable Indicators of Testicular Toxicity: Inhibin B, microRNAs, and Sperm Signatures (K Boekelheide, B McIntyre, M Coulson, R E Chapin)
  • Abstract #26
    Biomarkers of Testicular Injury: Where Have We Been (B McIntyre)

Bioinformatics and Computational Toxicology: Systems and Strategies

9:30 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #115, Poster Board #201
    Effect of Technical Variation and Bioinformatics on the Biological Discovery in a Mechanistic Toxicogenomics Study (B Gong, J Xu, Z Su, H Hong, J Meehan, H Fang, W Ge, S S Auerbach, C Wang, L Shi, W Tong)
  • Abstract #127, Poster Board #213
    Compound Toxicity Profiling and Prioritization Using Tox21 Phase I Quantitative High-Throughput Screening (qHTS) Cytotoxicity Data (J Hsieh, A Sedykh, R Huang, M Xia, R R Tice)
  • Abstract #144, Poster Board #230
    Modelability of ToxCast Phase I Datasets (A Golbraikh, A Sedykh, E Muratov, R Shah, W A Boyd, M Smith, G Zhao, H Zhu, J H Freedman, A Tropsha)

Biotransformation/Cytochrome P450

9:30 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #303, Poster Board #522
    Metabolism and Disposition of 2-Ethylhexyl-P-Methoxycinnamate in Male and Female Harlan Sprague-Dawley Rats and B6C3F1/N Mice after Gavage and Intravenous Administration (S Waidyanatha, R Snyder, Y Hong, S Watson, S Black, B McIntyre, J Mathews)
  • Abstract #308, Poster Board #527
    Metabolism and Disposition of Bisphenol AF in Male and Female Harlan Sprague-Dawley Rats following Gavage and Intravenous Administration (T Fennell, R Snyder, P Patel, S Black, J Mathews, M Mercado-Feliciano, S Waidyanatha)
  • Abstract #309, Poster Board #528
    Absorption, Distribution, Metabolism, and Excretion Studies of n-Butylbenzenesulfonamide in Harlan Sprague-Dawley Rats following Gavage Administration (S Black, S Watson, J Mathews, C Rider, S Waidyanatha)

Inflammation and Disease

9:30 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #258, Poster Board #452
    Role of Mannose-Binding Lectin in the Pulmonary Response to Ozone (J Ciencewicki, K E Gerrish, P Bushel, S R Kleeberger)

Inhalants and Cardiopulmonary

9:30 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #209, Poster Board #452
    Gene Expression in Bronchiolitis Obliterans-Like Lesions in Rats Exposed to 2,3-Pentanedione (D L Morgan, B A Merrick, K E Gerrish, P S Stockton, J F Foley, W M Gwinn, G P Flake)
  • Abstract #226, Poster Board #520
    An In Vitro Cell-Based Assay to Measure the Solubilization of Indium-Containing Particles by Macrophages (W M Gwinn, W Qu, R W Bousquet, M P Waalkes, D L Morgan)

Meet the Directors (L Birnbaum)

1:00 PM - 3:30 PM, Grand Ballroom C1 (CC), Featured Session

 

Chemical Mixtures

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #564, Poster Board #564
    Evaluation of Additivity of Binary Mixtures of Perfluoroalkyl Acids (PFAAs) on Peroxisome Proliferator-Activated Receptor-Alpha (PPARα) Activation In Vitro (C J Wolf, C Rider, C Lau, B D Abbott)
  • Abstract #578, Poster Board #431
    Generalized Concentration Addition Models Some but Not All Interactions of Mixtures of Androgen- and Estrogen-Receptor Active Compounds in High-Throughput Screening Assays (F Parham, M , R Huang, M Xia, B Collins, C Rider, R R Tice)
  • Abstract #581, Poster Board #434
    Chemical Characterization of Complex Aromatic Flame Retardants for Toxicological Studies (R Harris, M Kroenke, J Van Scoy, Q Lawrence, B O'Brien, A Ammenhauser, L Siemann, K Aillon, J Algaier, B Collins, S Waidyanatha)
  • Abstract #582, Poster Board #435
    Preparation of Toxicological Studies: Principal Component Analysis of Isopropylated Phenol Phosphate (J Algaier, M Kroenke, L Lucas, K Bauer, K Aillon, L Siemann, R Harris, B Collins, S Waidyanatha)

Epigenetics

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #526, Poster Board #345
    Epigenetics of Arsenic Carcinogenesis and Location of Methylated DNA Sites Underlying Gene Expression Changes (B Alex Merrick, E J Tokar, D P Phadke, R R Shah, M Wang, O Gordon, G M Wright, M Burke, S A Baxter, K E Pelch, R R Tice, M P Waalkes)
  • Abstract #529, Poster Board #348
    Chromatin Context Modulates Genome-Wide p53 Sequence-Specific Occupancy and Exposure-Induced Gene Expression (D A Bell, D Su, M R Campbell, X Wang)

Liver

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #643, Poster Board #518
    Leptin Modulates Toxicity Associated Steatohepatitis through Peroxynitrite in Kupffer Cells (S Das, A Kumar, D Ganini, E J Tokar, J Corbett, M Kadiiska, M P Waalkes, A Diehl, R P Mason, S Chatterjee)

Nanotoxicology-Carbonaceous Materials

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #433, Poster Board #208
    Loss of Epithelial Monolayer Integrity following Exposure of Primary Human Airway Cells to Multiwalled Carbon Nanotubes (R J Snyder, S Hussain, R Wine, J Roberts, J M Brown, N J Walker, S Garantziotis)

Pharmacokinetics and Disposition

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #484, Poster Board #302
    Disposition and Kinetics of Tetrabromobisphenol a (TBBPA) in Female Wistar-Han Rats (G A Knudsen, J M Sanders, A M Sadik, L S Birnbaum)
  • Abstract #487, Poster Board #305
    Dose-Response Relationship of an Environmental Mixture of Pyrethroids following an Acute Oral Administration in the Rat (M F Hughes, D G Ross, J M Starr, E J Scollon, M J Wolansky, K M Crofton, M DeVito)
  • Abstract #489, Poster Board #307
    Preliminary Toxicokinetics of N-butylbenzenesulfonamide after a Single Intravenous or Gavage Administration to Harlan Sprague-Dawley Rats and B6C3F1/N Mice (S Hong, S Gibbs, S Graves, D Kobs, C Rider, A Martone, S Waidyanatha)
  • Abstract #491, Poster Board #309
    Characterization of the Fate of β-Hexabromocyclododecane (HBCD) in Mice (J M Sanders, G A Knudsen, A M Sadik, L S Birnbaum)
  • Abstract #495, Poster Board #313
    Analysis of tris(2-Chloroisopropyl)phosphate Metabolites in Rat Plasma for Toxicology Studies (B Collins, S Waidyanatha, M Stout, A Gutierrez, R Mathias, C Dillon, D Slade, C Croutch, K Aillon, J Algaier, R Harris)
  • Abstract #500, Poster Board #318
    Accumulation of β-N-Methylamino-L-Alanine in Tissues following Repeat Oral Administration to Harlan Sprague-Dawley Rats (C Garner, C J Wegerski, M Doyle-Eisele, J Lucak, S Waidyanatha, J D McDonald, J M Sanders)
  • Abstract #502, Poster Board #320
    Development of Sustained Release Buprenorphine for Use as an Improved Analgesic in Toxicology Studies: Assessment of Formulation Pharmacokinetics (L Koetzner, W Stokes, W Lance, G Wnorowski, N South, J Boulet)
  • Abstract #513, Poster Board #331
    Comparative Disposition and Metabolism of 2, 2’-Dithiobisbenzanilide following Dermal, Oral, and Intravenous Administration to Harlan Sprague-Dawley Rats and B6C3F1/N Mice (J Lucak, C Garner, C J Wegerski, J M Sanders, M Doyle-Eisele, J D McDonald, S Waidyanatha)

Pharmacokinetics and Disposition (cont’d)

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #514, Poster Board #332
    Effect of Vehicle on the Dermal Absorption of 2-Hydroxy-4-Methoxybenzophenone Harlan Sprague-Dawley Rats and B6C3F1/N Mice (C J Wegerski, C Garner, M Doyle-Eisele, J M Sanders, J D McDonald, S S Auerbach, S Waidyanatha)

Biomonitoring: Emerging Markers and Methods

2:00 PM - 4:45 PM, Room 206 (CC), Platform Session, Chair: M Kadiiska

  • Abstract #801
    Antioxidants and Oxidative Modification of Biomolecules: Can They Identify a Biomarker of Ozone Oxidative Stress? (M Kadiiska)

Life-Course Models for Ensuring Children’s Health Protection

2:00 PM - 4:45 PM, Room 214 A&B (CC), Workshop Session, Speaker P M Foster

  • Abstract #784
    New Strategies for Addressing Toxicity Testing across the Lifespan (P M Foster)

Mode of Action and Human Relevance of Rodent Tumors

2:00 PM - 4:45 PM, Room 205 (CC), Platform Session

  • Abstract #806
    Liver Effects in CD1 Mice Prenatally-Exposed to Low Doses of Perfluorooctanoic Acid (PFOA): Novel Modes of Action (S E Fenton, A J Filgo, C A Cummings, M Hoenerhoff, D Malarkey, E M Quist)

Toxicity of Nanoparticles—Cerium Oxide

2:00 PM - 4:45 PM, Room 207 (CC), Platform Session, Chair N J Walker

  • Abstract #817
    Mechanistic Insights into the Toxicity of Multiwalled Carbon Nanotubes and Cerium Dioxide Nanoparticles in Primary Human Bronchial Epithelial Cells (S Hussain, R Snyder, S M Anderson, J D Marshburn, A B Rice, N J Walker, S Garantziotis)


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Tuesday, March 12

The Dynamics of Neuroinflammation and Inflammatory Cell Responses in Neurologic Disease

9:00 AM - 11:45 AM, Room 217 C&D (CC), Symposium Session, Chair G J Harry

  • Abstract #832
    The Dynamics of Neuroinflammation and Inflammatory Cell Responses in Neurologic Disease (G Jean Harry, C P Curran)
  • Abstract #833
    Microglia Heterogeneity in Neuroinflammation and Neurotoxicity (G J Harry)

Alternative Models—Eye and Skin

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #964, Poster Board #345
    Performance Standards and Alternative Assays: Practical Insights from Skin Sensitization (D Basketter, S N Kolle, S Casati, W S Stokes, J Strickland, H Vohr, B van Ravenzwaay, R Landsiedel)

Biomarkers I: Preclinical and Translational Approaches

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #939, Poster Board #316
    Whole Transcriptome RNA-Seq of FFPE Liver (S S Auerbach, B A Merrick, R R Shah, D Phadk, B Xie, J Shin, Y Gao, R R Tice)

Carcinogenesis: Models and Mechanisms

Carcinogenesis: Models and Mechanisms

  • Abstract #1092, Poster Board #537
    Expression Profiles of Hematopoietic Stem Cell, Endothelial Cell, and Myeloid Cell Antigens in Spontaneous and Chemically Induced Hemangiomas and Hemangiosarcomas in Mice (S Kakiuchi-Kiyota, C A Torrie, L L Arnold, K L Pennington, J C Cook, D Malarkey, S M Cohen)
  • Abstract #1094, Poster Board #539
    Transcriptomic Profiling of Hepatoblastomas and Associated Hepatocellular Carcinomas in B6C3F1 Mice (S Bhusari, A Pandiri, Y Wang, J Foley, H Hong, T Ton, K R Shockley, S Peddada, K E Gerrish, D Malarkey, R Sills, M Hoenerhoff)
  • Abstract #883, Poster Board #134
    Quantitative Extrapolation of In Vitro Data to Risk Management Decisions: Using Hepatic Ah Receptor and Its Agonists as an Example (X Chang, M DeVito, M Easterling)
  • Abstract 985, Poster Board #402
    Integrating Genome and Transcriptome Data to Understand Susceptibility to Postnatal Lung Injury (J Nichols, A Burkholder, J Lu, Z McCaw, O Suzuki, D Fargo, P Bushel, T Wiltshire, S R Kleeberger)
  • Abstract #986, Poster Board #403
    Analysis of the Developmental Origins of Health and Disease (DOHaD) Grant Portfolio at the NIEHS (A Haugen, T T Schug, J J Heindel)

Developmental Toxicity

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1015, Poster Board #434
    Addressing the Mode of Action for Developmental PFOA-Induced Mammary Gland Delays (M B Macon, S E Fenton)
  • Abstract #1019, Poster Board #438
    Development and Validation of an Analytical Method for Monobutylphthalate, a Metabolite of Di-n-Butylphthalate, in Harlan Sprague-Dawley Rat Plasma and Amniotic Fluid by UPLC-MS/MS (V G Robinson, M A Silinski, T A Freed, R A Fernando, C S Smith, S Waidyanatha)

Metals I

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1153, Poster Board #605
    The Cadmium-Responsive Genes Numr-1 and Numr-2 Are Regulated by Multiple Pathways (Q Ding, J H Freedman)
  • Abstract #1157, Poster Board #609
    Cadmium Exposure Affects Insulin Signaling in Caenorhabditis elegans (Y Sun, J H Freedman)
  • Abstract #1175, Poster Board #452
    Development and Optimization of a Procedure for the Determination of Indium-Tin Oxide Particle Size and Concentration in Cellular Media (K Levine, L Han, W M Gwinn, D L Morgan, A S Essader, R A Fernando, C S Smith, V G Robinson)
  • Abstract #1187, Poster Board #452
    Metallothionein Transcriptional Regulation, Aging, and the Insulin Signaling Pathway (J Hall, M McElwee, J H Freedman)
  • Abstract #1188, Poster Board #452
    Metal-Regulatory Transcription Factor-1 Regulates Metal-Responsive Transcription of Fosl1 (E Braithwaite, J H Freedman)

Research Funding Information Room

9:30 AM - 4:30 PM, Room 209 (CC)

  • NIEHS Division of Extramural Research and Training

Alternative High-Throughput Models I

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1450, Poster Board #507
    A High-Throughput Mechanism-Based Toxicity Screen Using C. elegans (R B Goldsmith, J R Pirone, W A Boyd, M V Smith, J H Freedman)
  • Abstract #1452, Poster Board #509
    Quantitative Assessment of Phase II ToxCast™ Chemical Toxicity in C. elegans (W A Boyd, M V Smith, J R Pirone, J R Rice, J H Freedman)

Natural Products - In Vivo Safety Assessment

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1300, Poster Board #302
    Toxicology Profile of Virginia Cedarwood Oil Delivered via Dermal Application (I Surh, R A Herbert, G S Travlos, M Vallant, L M Fomby, M R Hejtmancik, P Chan)

Pharmaceutical Safety Assessment: Drug Development II

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1227, Poster Board #139
    Immunomodulatory Activity of Orphan Drug Elmiron® in Female B6C3F1/N Mice (S Thakur, N Abraham, K L White, M J Smith, W Auttachoat, D R Germolec)

Regulatory Policy: Programs and Approaches

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1570, Poster Board #631
    A New Approach to Academic and Guideline Research: The CLARITY-BPA Research Program (A F Johnson, J Aungst, J R Bucher, C Luisa, K Delclos, J J Heindel, P C Howard, D Keefe, R Newbold, W Nigel, T T Schug)
  • Abstract #1572, Poster Board #633
    Animal Use for Testing Involving Unrelieved Pain and Distress (M Paris, L Rinckel, W Casey, W Stokes)
  • Abstract #1573, Poster Board #634
    A Reference Database for the Evaluation of Alternative Tests for Acute Dermal Systemic Toxicity (J Strickland, F Stack, M Paris, L Rinckel, W Casey, W Stokes)
  • Abstract #1574, Poster Board #635
    Regulatory Acceptance of the BG1Luc Estrogen Receptor Transactivation Test Method (W Casey, P Ceger, J Strickland, L Rinckel, E Grignard, S Bremer, H Kojima, S Han, W Stokes)
  • Abstract #1576, Poster Board #637
    The Dermal Up-And-Down Procedure: An Alternative Test Method for Acute Dermal Systemic Toxicity Testing (W Stokes, J Strickland, R Morris, L Ho, J Wilkerson, F Stack, M Paris, L Rinckel, W Casey)

Stems Cells: Emerging Applications in Toxicology

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1191, Poster Board #103
    Hypersensitivity of Stem Cells and Cancer Stem Cells to Cadmium Toxicity (E J Tokar, M Rogers, M P Waalkes)
  • Abstract #1192, Poster Board #104
    Recruitment of Normal Stem Cells into an Oncogenic Phenotype by Noncontiguous Carcinogen-Transformed Malignant Epithelia Is Dependent on the Transforming Carcinogen (Y Xu, E J Tokar, R J Person, R Orihuela, M P Waalkes)
  • Abstract #1193, Poster Board #105
    Aberrant microRNA Expression Correlates with RAS Activation in Malignant Transformation of Human Prostate Epithelial and Stem Cells by Arsenic (N N Ngalame, E J Tokar, M P Waalkes)

Nonmonotonic Dose-Response Curves and Endocrine-Disrupting Chemicals: Fact or Falderal?

1:30 PM - 4:15 PM, Grand Ballroom C2 (CC), Symposium Session, Chair P M Foster

  • Abstract #1592
    Nonmonotonic Dose-Response Curves and Endocrine-Disrupting Chemicals: Fact or Falderal? (L E Gray, P M Foster)
  • Abstract #1597
    Low Dose and Nonmonotonic Dose-Response Curves for Endocrine Disruptors (L S Birnbaum)

Implementing Systematic Review at the NTP: Presented by National Toxicology Program

2:45 PM - 3:45 PM, Room 007 B (CC), Exhibitor Hosted Session, Andrew Rooney and Abee Boyles

 

The Symbiosis of Mentoring: Getting the Most Out of the Mentor-Mentee Relationship

4:30 PM – 5:50 PM, Room 214 A&B (CC), Education-Career Development Session, Speaker N Walker

  • Abstract #1630
    The Symbiosis of Mentoring: Getting the Most Out of the Mentor-Mentee Relationship (B Hannas, N Walker, S Safe, E Carney, O Olivero)
  • Supervisors, Mentors and Yodas: A Perspective on Their Role in Your Career Development (N J Walker)

Tox ShowDown (L S Birnbaum)

7:30 PM - 9:00 PM, Alamo Ballroom D (Marriott Riverwalk)

 


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Wednesday, March 13

Role of Systems Biology in Characterizing Risk of Developmental Origins of Disease

9:00 AM - 11:45 AM, Grand Ballroom C2 (CC), Symposium Session

  • Abstract #1633
    Multiple Organ-Omic Integration for HBCD Developmental Neurotoxicity Hazard Identification (D T Szabo, L S Birnbaum)
  • Abstract #1635
    Mechanistic Pathways Underlying Low-Dose PFOA Effects on Mammary Gland Growth (M B Macon, S E Fenton)

Children's Health and Juvenile Toxicity

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1828, Poster Board #358
    Maternal and Child Polybrominated Diphenyl Ether (PBDE) Levels in US National Children’s Study (NCS) Formative Research (A J Schecter, D Cherry, L S Hynan, D Cheng, N Imran, M Hommel, K Kannan, L Wang, S H Yun, N Thiex, B Specter, J Moye, L S Birnbaum)

Endocrine Toxicology

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1934, Poster Board #521
    Formulation Development and Analysis Methods for Bisphenol AF in 5K96 Verified Casein Feed (K Aillon, V Ault, A Sullivan, R Mathias, J Algaier, R Harris, B Collins, S Waidyanatha)

Genetic Toxicology and DNA Repair

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1701, Poster Board #116
    Comparison of Two High-Throughput Methods for In Vitro Micronucleus Assessment (B Goodwin, J Bemis, Z Liu, S Bryce, K Luu, K L Witt, C P Austin, R R Tice, M Xia)

Nanotoxicology-In Vitro

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract 1751, Poster Board #218
    The Effects of Ceria Nanoparticles on Primary Human Monocyte-Derived Macrophages and Bronchial Macrophages (J D Marshburn, A B Rice, M D George, S M Anderson, N J Walker)

Persistent Organic Pollutants

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1982, Poster Board #572
    Structure-Activity Relationships for Perfluoroalkane-Induced Interference with Rat Liver Mitochondrial Respiration (K B Wallace, G E Kissling, R Melnick, C R Blystone)
  • Abstract #1992, Poster Board #582
    Alterations in Xenobiotic Metabolizing Enzyme and Immune Relevant Genes following Administration of Brominated and Chlorinated Dioxins and Furans in Female B6C3F1 Mice (R Frawley, M Smith, K White Jr, N J Walker, L S Birnbaum, T Maynor, M DeVito, D R Germolec)
  • Abstract #1999, Poster Board #589
    Development of Weighted Distributions of Relative Potency Estimates for Dioxin-Like Compounds (L C Haws, G Hixon, M DeVito, N J Walker, L Kuriakose, L S Birnbaum, M Harris, D Wikoff)

Risk Assessment II: Critical Considerations and Characterizations

9:00 AM - 12:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #1944, Poster Board #534
    Benchmark Dose Models for Benzene Genotoxicity Using the Diversity Outbred Mouse (K L Witt, G E Kissling, D L Morgan, K R Shockley, D M Gatti, G A Churchill, J E French)
  • Abstract #1957, Poster Board #547
    The Use of Genetically Modified Mice in Cancer Risk Assessment: Challenges and Limitations (S V Vulimiri, D A Eastmond, J E French, B Sonawane)

Research Funding Information Room

9:30 AM - 4:30 PM, Room 209 (CC)

  • NIEHS Division of Extramural Research and Training

Alternative High-Throughput Models II

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #2251, Poster Board #449
    Comparison of the Manual and Quantitative High-Throughput Versions of the BG1Luc Estrogen Receptor Transactivation Test Method (P Ceger, W Casey, J Strickland, L Rinckel, W Stokes)
  • Abstract #2269, Poster Board #467
    Use of a Cell-Based Assay to Monitor the Stability of the Tox21 10K Compound Library (R Huang, J Zhao, M Xia, K L Witt, K Houck, R R Tice, D Dix, C P Austin)
  • Abstract #2275, Poster Board #473
    In Vitro to In Vivo Extrapolation Using Data from ToxCast (M DeVito, S S Auerbach, A Merrick, K L Witt, K Janardhan, D Malarkey, H Nagai, I Shah, C Corton, R Judson)

Arsenic

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #2280, Poster Board #503
    Comparative Early Oncogenic Effects of Cadmium and Arsenic in Human Lung Epithelial Cells (R J Person, E J Tokar, M P Waalkes)
  • Abstract #2281, Poster Board #504
    Metallothionein Blocks Arsenic-Induced Oxidative DNA Damage (W Qu, M P Waalkes)

Food Safety and Nutrition

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #2326, Poster Board #553
    Development and Validation of an Analytical Method for Vomitoxin in Gavage Dose Formulations Used in Rodent Toxicology Studies (J C Blake, D P Coleman, J Gilliam, M A Silinski, R A Fernando, C S Smith, B Collins, V G Robinson)

Male Reproductive Toxicology

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • Abstract #2127, Poster Board #240
    Simvastatin and Dipentyl Phthalate Lower Testosterone Production and Exhibit Dose Additive Effects on the Fetal Testis via Distinct Mechanistic Pathways (B Beverly, C Lambright, J R Furr, H Sampson, B McIntyre, P M Foster, G S Travlos, V S Wilson, L E Gray)

Exposure Science in the 21st Century: Perspectives from the NAS and What It Means for Toxicology

4:30 PM - 5:50 PM, Room 214 A&B (CC), Informational Session, Chair and Speaker L S Birnbaum

  • Abstract #2463
    Exposure Science in the 21st Century: Perspectives from the NAS and What It Means for Toxicology (L S Birnbaum, J Orme-Zavaleta)

SOT President's Reception

7:00 PM - 8:30 PM, Lone Star Ballroom B (Grand Hyatt)

 


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Thursday, March 14

Cumulative Risk: Toxicity and Interactions of Physical and Chemical Stressors

9:00 AM - 11:45 AM, Room 217 A&B (CC), Workshop Session, Chair C Rider

  • Abstract #2497
    Cumulative Risk: Toxicity and Interactions of Physical and Chemical Stressors (J Simmons, C Rider)

From Immunotoxicity to Nanotherapy: The Effects of Nanomaterials on the Immune System

9:00 AM - 11:45 AM, Grand Ballroom C2 (CC), Symposium Session, Chair N J Walker

  • Abstract #2466
    From Immunotoxicity to Nanotherapy: The Effects of Nanomaterials on the Immune System (M J Smith, D R Germolec, N J Walker)
  • Abstract #2467
    Overview of Concepts and Strategies Needed for Assessing the Safety of Nanoscale Materials (N J Walker)
  • Abstract #2469
    Evaluating the Local and Systemic Immunomodulatory Effects of Nanomaterials (M J Smith, D R Germolec, C E McLoughlin, W Auttachoat, K L White)

Modeling Human Genetic Variability and Susceptibility in the Laboratory

9:00 AM - 11:45 AM, Room 217 C&D (CC), Symposium Session, Chair R Woychik

  • Abstract #2472
    Modeling Human Genetic Variability and Susceptibility in the Laboratory (R Woychik, D Threadgill)
  • Abstract #2474
    The Use of Population-Based Inbred Panels and Diversity Outbred Mouse Models to Explore Individual Variability and Toxicity to Benzene (J E French)

Late Breaking Poster Session 3

1:00 PM - 4:30 PM, Exhibit Hall C-D (CC), Poster Session

  • PBDEs, PCBs, TEQs, Dioxins, Metals and Persistent Pesticide Exposure in Female Vietnamese Electronic Waste Recyclers (A Schecter, H T Quynh, A Sjodin, K Caldwell, D Cheng, T T Tuyet-Hanh, M Hommel, N Imran, L S Birnbaum)


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