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Associate Director, National Toxicology Program

The NTP associate director assists the NIEHS/NTP director with overseeing the day-to-day operations of the National Toxicology Program, which is headquartered at the NIEHS in Research Triangle Park, North Carolina.


The is an interagency program established in 1978 by the Secretary of Health, Education and Welfare, which today is known as the U.S. Department of Health and Human Services. The program was created as a cooperative effort to coordinate toxicology testing programs within the federal government, strengthen the science base in toxicology, develop and validate improved testing methods, and provide information about potentially toxic chemicals to health, regulatory, and research agencies, scientific and medical communities, and the public. provide regular external input to the program on its activities and policies, ensuring their high quality and relevance.


John R. Bucher serves as both NTP associate director, and as director of the National Toxicology Program Division("/Rhythmyx/assembler/render?sys_contentid=54353&sys_revision=4&sys_variantid=1169&sys_context=0&sys_authtype=0&sys_siteid=&sys_folderid=" sys_dependentvariantid="1169" sys_dependentid="54353" inlinetype="rxhyperlink" rxinlineslot="103" sys_dependentid="54353" sys_siteid="" sys_folderid="").

Bucher  is an internationally recognized expert in the design and interpretation of cancer bioassays, and has authored a number of important publications examining critical issues in dose selection for toxicology and cancer studies.


John R. Bucher, Ph.D.
John R. Bucher, Ph.D.
Associate Director, National Toxicology Program
Director, National Toxicology Program Division
Tel (919) 541-4532
Fax (919) 541-4255
bucher@niehs.nih.gov
P.O. Box 12233
Mail Drop K2-02
Research Triangle Park, North Carolina 27709
Delivery Instructions


Bucher joined the NTP as a toxicologist in 1983 and since then has played a key role in shaping the program’s research and policies. In 2007, he was named NTP Associate Director("/Rhythmyx/assembler/render?sys_contentid=17319&sys_revision=1&sys_variantid=610&sys_context=0&sys_authtype=0&sys_siteid=&sys_folderid=" sys_dependentvariantid="610" sys_dependentid="17319" inlinetype="rxhyperlink" rxinlineslot="103" sys_dependentid="17319" sys_siteid="" sys_folderid="") where he began to oversee the day to day operations of the program. Bucher has been instrumental in preparing the program to meet the needs of the 21th century. For example, in 2008 he co-authored a in the journal, Science, which describes a way to transform toxicology by taking advantage of new technologies and shifting protocols for toxicity assessments from laboratory animal studies to more cell-based tests.


Bucher holds a doctorate in pharmacology from the University of Iowa, a Master of Science in biochemistry from the University of North Carolina at Chapel Hill, and a Bachelor of Arts in biology from Knox College.

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